scirrhous


Also found in: Dictionary, Encyclopedia.
Related to scirrhous: scirrhous carcinoma, scirrhous cord

scirrhous

 [skir´us]
hard or indurated.

scir·rhous

(skir'us, sir'), Avoid the misspellings schirrous and schirrhous. Do not confuse this word with serous.
Hard; relating to a scirrhus.

scirrhous

/scir·rhous/ (skir´us) hard or indurated; see under carcinoma.

scirrhous

adjective From the Greek skirrhos, for gypsum:
(1) Hardened, indurated;
(2) Referring to the dense stroma seen in cancers that produce abundant connective tissue. Scirrhous induration (SI) or “desmoplastic reaction” is typical of ductal carcinoma of the breast, which is often accompanied by microcalcifications; SI also occurs in pancreas adenocarcinoma.

scirrhous

skirrhos, Greek, gypsum adjective Relating to a dense stroma seen in some CAs, which produce abundant connective tissue; scirrhous induration–SI or 'desmoplastic reaction' is typical of ductal CA of breast, often accompanied by microcalcifications; SI also occurs in pancreas adenoCA.

scir·rhous

(skir'ŭs)
Hard; relating to a scirrhus.

scirrhous

Hard and fibrous, especially of malignant tumours containing dense fibrous tissue.

scirrhous

hard or indurated.

scirrhous carcinoma
carcinoma with a hard structure owing to the formation of dense connective tissue in the stroma.
scirrhous cord
see scirrhous cord.
References in periodicals archive ?
Relationship of p53 and vascular endothelial growth factor expression of clinicopathological factors in human scirrhous gastric cancer.
Long-standing scirrhous breast carcinoma en cuirasse.
Primary scirrhous adenocarcinoma of the stomach spreads predominantly in the submucosa and muscularis propria.
2) The author noted that "the histologic character of cancer of the prostate is very variable" and described acinar, scirrhous, and solid patterns of growth.
An advanced tumor at the cardia may be manifested on barium studies by a polypoid or ulcerated mass in this region or by an infiltrating or scirrhous lesion encasing the gastric fundus (Figure 5B).
19, 20) The high sensitivity of Arg-1 was also observed in poorly differentiated HCC (95% in our study, which is similar to the 90% reported by Yan et al (13)) as well as in scirrhous HCC.
2,8) One important exception is scirrhous adenocarcinoma, a tumor that infiltrates the submucosa and muscularis but spares the mucosa (2) By comparison, heterogeneous wall attenuation and enhancement, in which low-attenuation and high-attenuation areas do not conform to the bowel-wall layers, is suggestive of malignancy.
Variants of hepatocellular carcinoma such as scirrhous type and those with sarcomatoid features are sometimes difficult to distinguish from UESL.
Scirrhous HCC is a rare morphologic variant, composed of less than 5% of HCCs.
These 4 specimens were extremely fibrotic (eg, scirrhous breast carcinomas), exhibited marked necrosis, or were small lesions that were difficult to scrape.
In 1931, Craciun et al[4] reported the case of a woman who had had radical mastectomy for scirrhous carcinoma of the breast 14 months before her final presentation.
11] In another report, published in 1985 and dealing with 62 cases that presented during pregnancy, more than 60% of the cases were reported as grade III or IV scirrhous adenocarcinoma (Broders classification).