scavenger receptor


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scavenger receptor

a receptor on macrophages that binds preferentially to oxidized LDL, causing macrophages to internalize the LDL.
Farlex Partner Medical Dictionary © Farlex 2012

scav·en·ger re·cep·tor

(skav'ĕn'jĕr rĕ-sep'tŏr)
A receptor on macrophages that binds preferentially to oxidized low-density lipoprotein (LDL), causing macrophages to internalize the LDL.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Inflammatory cells are subsequently recruited to the arterial wall, such as monocytes, which differentiate into macrophages and are, as a result, activated to engulf oxidized LDL via scavenger receptors, creating foam cells, which secrete chemokines and other kinds of cytokines that further create a vicious cycle, more immune cell infiltration, and activation [13].
Huang et al., "High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells," Cardiovascular Diabetology, vol.
Hobbs, "Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat," The Journal of Clinical Investigation, vol.
Buehler, "Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a scavenger receptor," Antioxidants & Redox Signaling, vol.
Nauwynck, "Scavenger receptor CD163, a jack-of-all-trades and potential target for cell-directed therapy," Molecular Immunology, vol.
Moller, "Soluble haemoglobin scavenger receptor (sCD163) in patients with suspected community-acquired infections," APMIS, vol.
LDLR: low-density lipoprotein receptor; SCARB: scavenger receptor B; HMGCR: HMG-CoA reductase; CETP: cholesteryl ester transfer protein.
Association of three polymorphisms of scavenger receptor class BI gene (exon8, exon1, intron5) with coronary stenosis in a coronary Tunisian population.
CD163 is an Hb scavenger receptor exclusively expressed in the cell's monocyte/macrophage system.
van Berkel, "Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport atherosclerosis," Current Opinion in Lipidology, vol.
Endocytic uptake of advanced glycation end products by mouse liver sinusoidal endothelial cells is mediated by a scavenger receptor distinct from the macrophage scavenger receptor class A.