A cancer often located in the pulmonary apices and associated with pre-existing scars, wounds or inflammation–eg, healed TB, infarcts, abscess cavities, bronchiectasis, and metallic foreign bodies–eg, bullets; 80% of SCs are adenoCAs, 15% are SCCs, the rest are of other histopathologic types. See Passenger/driver controversy.
Ischemia is also implicated in the pulmonary scar cancers. Kolin and Koutoulakis studied the pathogenesis of scars in 57 consecutively resected, small ([is less than or equal to] 3 cm) peripheral lung cancers.
Role of arterial occlusion in pulmonary scar cancers. Hum Pathol.