saxitoxin


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saxitoxin

 [sak´sĭ-tok″sin]
a powerful heat-stable low molecular weight neurotoxin synthesized and secreted by certain dinoflagellates, such as species of Gonyaulax, which accumulates in the tissue of bivalve mollusks feeding on the dinoflagellates; it may cause a severe toxic reaction called shellfish poisoning in those who ingest contaminated mollusks.

sax·i·tox·in

(sak'si-tok'sin),
A potent neurotoxin found in shellfish, such as the mussel or the clam (and sometimes the pufferfish, Sphoerides nephelus), produced by the dinoflagellate Gonyaulax catenella, which is ingested by the shellfish; the cause of cases of poisoning from eating the California sea mussel (Mytilus californianus), scallop, and the Alaskan butterclam (Saxidomus giganteus).

saxitoxin

/saxi·tox·in/ (sak´sĭ-tok″sin) a powerful neurotoxin synthesized and secreted by certain dinoflagellates, which accumulates in the tissues of shellfish feeding on the dinoflagellates and may cause a severe toxic reaction in persons consuming contaminated shellfish.

saxitoxin

(săk′sĭ-tŏk′sĭn)
n.
A potent neurotoxin produced by certain dinoflagellates that accumulates in shellfish feeding on these organisms and consequently causes food poisoning in humans who eat the shellfish.

saxitoxin

[sak′sitok′sin]
a powerful neurotoxin found in bivalve mollusks, including mussels, clams, and scallops. It is produced by certain species of dinoflagellates, which are consumed by the mollusks. Saxitoxin may cause a severe food intoxication in humans who eat the contaminated shellfish.
A potent paralyzing neurotoxin first isolated from the Alaskan clam—Saxidomus giganteus—which binds to the cell membrane’s Na+ channel, blocking depolarisation at the neuromuscular junction, and increasing permeability for Na+; the toxin is heat-stable, water-soluble and rapidly absorbed from the GI tract; as few as 6 contaminated clams may be fatal

sax·i·tox·in

(sak'si-tok'sin)
A potent neurotoxin found in shellfish, such as the mussel or the clam, produced by the dinoflagellate Gonyaulax catenella, which is ingested by the shellfish; the cause of poisoning due to eating California sea mussels, scallops, and Alaskan butterclams.

saxitoxin

neurotoxic tetrahydropurine of the paralytic shellfish poisoning (PSP) toxin group from poisonous mussels, clams and plankton; a sodium channel blocker with the same mode of action as tetrodotoxin; originates in some toxic dinoflagellates and in some anabaena spp.
References in periodicals archive ?
A reinvestigation of saxitoxin production and sxtA in the 'non-toxic' Alexandrium tamarense Group V clade.
Toxins bound to MB were detected with a commercial kit for saxitoxin detection in solution (Ridascreen Fast PSP SC, R"Biopharm AG, Germany) according to manufacturer instructions.
As Hoffmann described it, Wertheim's method of synthesizing saxitoxins was extremely simple, the sort of thing that is obvious with hindsight (Hoffmann, 2006).
The two parent structures of the PSP family are saxitoxin and the N-hydroxylated compound neosaxitoxin.
Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP.
The team looked at blooms of Alexandrium catenella, more commonly known as "red tide," which produces saxitoxin, a poison that can accumulate in shellfish.
The freshwater cyanobacterium Lyngbya wollei forms dense mats in culturally impacted aquatic systems in Alabama and produces saxitoxin, a carbamate alkaloid neurotoxin.
El quimico mostraba su ingenio en la fabricacion de productos tan letales, como el gas sarin, el soman, el tabum, la clostridium botulinica, el saxitoxin y la tetrodotoxina.
ciguatoxin [the toxin of ciguatera] or saxitoxin [the toxin of paralytic shellfish poisoning]), and cyanobacterial toxins (e.
Shellfish toxicity level in the affected areas is above the regulatory limit of 60 microgram saxitoxin (ugSTXeg)/100 grams of shellfish meat.
EC Regulation 853/2004 describes the statutory limits of PST in flesh with the maximum permitted limit (MPL) of 800 (ag saxitoxin equivalents (STX eq.