To our knowledge, this study first demonstrated the interference of LXR[alpha] on bovine muscle
satellite cells in vitro to investigate LXR[alpha] gene's function and its target genes.
Isolation, culture and identification procedures of the porcine skeletal
satellite cellsMany growth factors, such as insulin-like growth factor 1, hepatocyte growth factor, epidermal growth factor, transforming growth factors, and platelet-derived growth factors, as well as cytokines, have been identified as causing proliferation of
satellite cells, with subsequent transformation into myotubes and muscle fibers, to regulate myoblast proliferation and differentiation, and to muscle regeneration or repair [9].
Undernutrition impairs the proliferation of
satellite cells resulting in muscle atrophy and myonuclei decrease (Carlson and Faulkner, 1988; Dedkov et al.
Kadi F, Thornell LE, 2000, Concomitant increases in myonuclear and
satellite cell content in female trapezius muscle following strength training.
Muscle
satellite cells and endothelial cells: close neighbors and privileged partners," Molecular Biology of the Cell, vol.
The purpose of this study was to investigate the effect of MENS on the regeneration process of injured skeletal muscle and to investigate whether
satellite cells in injured skeletal muscle are activated by MENS.
However, when they surgically conjoined old and young mice so that they shared blood, the
satellite cells in the old mice exhibited "restored genomic integrity.
We identified
satellite cells in muscle specimens by labeling Pax7 (1:50, Developmental Studies), a transcription factor specific for quiescent, activated, and proliferating
satellite cells.
In tests, the labA[degrees]grown muscle was found to be strong and good at contracting and was able to repair itself using the
satellite cells when the researchers damaged it with a toxin.
Every muscle has
satellite cells on reserve, ready to activate upon injury and begin the regeneration process.
Through years of perfecting their techniques, a team led by Bursac and graduate student Mark Juhas discovered that preparing better muscle requires two things: well-developed contractile muscle fibers and a pool of muscle stem cells, known as
satellite cells.
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