In this study, we found that LXR[alpha] genes were down-regulated by 88% after lentivirus infecting bovine muscle
satellite cells for 48h, the expression of ABCA1 and ApoE were also decreased.
Stratos and his coworkers [10] found that after a blunt muscle injury in animals, administration of G-CSF increased muscular regeneration by
satellite cell proliferation and decreased apoptosis.
Undernutrition impairs the proliferation of
satellite cells resulting in muscle atrophy and myonuclei decrease (Carlson and Faulkner, 1988; Dedkov et al., 2001).
Redox imbalance observed in senescent
satellite cells can be attributed to elevated ROS production or an impaired endogenous antioxidant defense system, leading to oxidative damage [7, 8].
Senba, "In vivo activation of STAT3 signaling in
satellite cells and myofibers in regenerating rat skeletal muscles," The Journal of Histochemistry and Cytochemistry, vol.
(b) High power (40x) showing ganglion cells (blue arrow) without rim of
satellite cells among Schwannian stroma (black arrow).
Isolation and characterization of primary skeletal muscle
satellite cells from rats.
Kadi F, Thornell LE, 2000, Concomitant increases in myonuclear and
satellite cell content in female trapezius muscle following strength training.
The main results in the preset work are: 1) there were muscle alterations in all the studied patients, including moderate to severe atrophy, necrosis, activation of
satellite cells, presence of autophagosomes and macrophage and mast cell infiltration.
However, when they surgically conjoined old and young mice so that they shared blood, the
satellite cells in the old mice exhibited "restored genomic integrity." Their
satellite cell DNA was indistinguishable from the DNA in young mice, the authors wrote.
We identified
satellite cells in muscle specimens by labeling Pax7 (1:50, Developmental Studies), a transcription factor specific for quiescent, activated, and proliferating
satellite cells.
The Duke University researchers say their success was down to creating the perfect environment for muscle growth A[degrees] wellA[degrees]developed contractile muscle fibres and a pool of immature stem cells, known as
satellite cells, that could develop into muscle tissue.