RYR1

(redirected from sarcoplasmic reticulum calcium release channel)

RYR1

A gene on chromosome 19q13.1 that encodes a ryanodine receptor found in skeletal muscle, which acts as a calcium channel connecting the sarcoplasmic reticulum and transverse tubules.

Molecular pathology
RYR1 mutations are linked to malignant hyperthermia susceptibility, central core disease and minicore myopathy with external ophthalmoplegia.
References in periodicals archive ?
Using an artificial bilayer system, the effect that gender plays on the opening characteristics of the rabbit sarcoplasmic reticulum calcium release channel was researched.