sarcomere


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sarcomere

 [sahr´ko-mēr]
the contractile unit of a myofibril; sarcomeres are repeating units, delimited by the Z bands along the length of the myofibril.
Thick and thin filaments are organized into contractile units called sarcomeres. A sarcomere extends from one Z line to the next and represents the fundamental unit of muscle contraction. From Copstead, 1995.

sar·co·mere

(sar'kō-mēr),
The segment of a myofibril between two adjacent Z lines, representing the functional unit of striated muscle.
[sarco- + G. meros, part]

sarcomere

/sar·co·mere/ (sahr´ko-mēr) the contractile unit of a myofibril; sarcomeres are repeating units, delimited by the Z bands, along the length of the myofibril.

sarcomere

(sär′kə-mîr′)
n.
One of the repeating contractile segments into which a myofibril is divided, composed of actin and myosin filaments and giving striated muscle its distinctive bands.

sarcomere

[sär′kōmir]
Etymology: Gk, sarx + meros, part
the smallest functional, contractive unit of a myofibril. Sarcomeres occur as repeating units, extending from one Z line to the next along the length of the myofibril.
enlarge picture
Sarcomere

sar·co·mere

(sahr'kō-mēr)
The segment of a myofibril between two adjacent Z lines, representing the functional unit of striated muscle.
[sarco- + G. meros, part]

sarcomere

The structural unit of a striped muscle fibre (myofibril).
Sarcomereclick for a larger image
Fig. 273 Sarcomere . Muscle fibrils consist of alternating groups of the thick and thin filaments (dark and light bands), the distance between two Z-membranes being termed a ‘sarcomere’.

sarcomere

that part of the muscle fibre which is contained between two Z-MEMBRANES, and is the contractile element of the fibre.

See MUSCLE, I-BAND.

sarcomere

length-wise repeating unit of striated muscle, from one Z line to the next; length about 2.5 × 10-6 in fully extended muscle, less in shortened. See also myofibrils.

sarcomere

the contractile unit of a myofibril; sarcomeres are repeating units, delimited by the Z bands along the length of the myofibril.
References in periodicals archive ?
With MyoKardia's platform, we have the ability to exquisitely characterize the biochemistry and biophysics of the human mutated sarcomere," said Dr.
1973), WBSF decreases exponentially as the sarcomere length increases but this correlation significant only for length lower than 2.
This strategy of tension release also led to a major defect in sarcomere and myofibril formation.
On the other hand, according to "sarcomere give' theory stretching of an active muscle causes a rapid increase of force after the onset of stretch, followed by a sudden yielding of the sarcomeres, which may affect subsequent muscle performance (Flitney and Hirst, 1978).
Williams PE, Goldspink G (1978) Changes in sarcomere length and physiological properties in immobilised muscle.
In addition, genes coding for proteins of the sarcomere (beta- and alpha-myosin heavy chain, troponin C, alpha tropomyosin, myosin binding proteins), which have important regulatory functions in animal biology and familial hyperthrophic cardiomyopathy in human (Ramirez & Padron 2004), may also have important regulatory functions in shrimp biology.
Genetically, HCM is a disease of the sarcomere that is an autosomal dominant disorder with a reported phenotypic prevalence of 1:500 based on population studies (2).
2) On ultrastructural exam, diagnosis is confirmed with identification of the spectrum of rhabdomyoblastic differentiation and rudimentary sarcomere formation consisting of Z bands or Z band material.
Sarcomere lesion damage occurs mainly in slow fibers of reloaded rat adductor longus muscles.
Drosophila melanogaster is being used as a model organism with which to study myofibril assembly and growth of the sarcomere in striated muscle.
It has an autosomal-dominant pattern due to missense mutations in sarcomere genes.
It is thought to be the result of mutations in any one of four components of the cardiac sarcomere.