saralasin


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saralasin

 [sar-al´ah-sin]
an angiotensin II antagonist, used in the form of the acetate ester as an antihypertensive in treatment of severe hypertension and in diagnosis of renin-dependent hypertension.

saralasin

/sar·al·a·sin/ (sar-al´ah-sin) an angiotensin II antagonist, used in the form of the acetate ester as an antihypertensive in the treatment of severe hypertension and in the diagnosis of renin-dependent hypertension.

saralasin

a competitive antagonist of angiotensin. It is administered by IV injection to assess the role of the renin-angiotensin system in the maintenance of blood pressure. A decrease in blood pressure is expected in renin-dependent hypertension.

saralasin

a competitive angiotensin II antagonist.
References in periodicals archive ?
Addition of saralasin (Ang II antagonist), however, could inhibit hCG-induced oocyte maturation (3).
In theca cells, there was no difference in mRNA expression for CYP17A1, HSD3B2 and STAR between dominant follicles treated with saralasin or vehicle during follicular deviation (FERREIRA et al.
Additionally, it was observed a significant decrease in mRNA abundance for the enzyme CYP19A1 in granulosa cells of dominant follicles after intrafollicular injection of saralasin (FERREIRA et al.
Indeed, the intrafollicular injection of saralasin in the dominant follicle did not reduce CYP17A1 expression, which is in agreement with findings in the present study showing that Ang II do not increase CYP17A1 mRNA expression in LH-treated cells.
The activation of the TF was reversed by saralasin, an antagonist of angiotensin II receptors.
Furthermore, hCG-induced oocyte maturation was inhibited by a concomitant addition of saralasin (an Ang II antagonist) (3)