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The aglycon of a saponin; one of a family of steroids of the spirostan type (a 16,22:22,26-diepoxycholestane).
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Therefore, this sapogenin could constitute an interesting approach for lung cancer therapy [31,37].
RYR also contains sterols including beta-sitosterol, campesterol, stigmasterol, sapogenin, isoflavones, monounsaturated fatty acids, decalins and other biphenolic compounds, azaphilones and other lactone ring compounds, GABA (gamma aminobutyric acid), dimerumic acid, and citrin.
Officigenin, a New Sapogenin of Guaiacum officinale J Nat Prod 1984;47:977-982.
Basically, chemical structure of saponins consists of a sugar moiety (glucose, galactose, glucoronic acid, xylose, rhamnose, or methylpentose) that glycosidically linked to a hydrophobic aglycone or sapogenin (Francis et al., 2002).
Diosgenin in fenugreek is a steroidal sapogenin and is one of the compounds of fenugreek extract which acts as cortisone, and consequently, reduces anxiety (19).
Phytoestrogens as diosgenin, a type of steroidal sapogenin, could explain the observed milk flow increase [3].
Barringtonia saponin and sapogenin. Archiv der Pharmazie, 289: 140-143.
They are characterized by the number of sugar chains attached to the triterpene or steroid aglycone backbone, also called sapogenin. While evidence has shown that the main dietary sources of saponins are the dicotyledon like legumes, the main non-food sources used in health and industrial applications include the soap bark tree, Medicago sativa, Aesculus hippocastanum and Glycyrrhiza glabra [5].