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The aglycon of a saponin; one of a family of steroids of the spirostan type (a 16,22:22,26-diepoxycholestane).
References in periodicals archive ?
Steroidal sapogenins such as diosgenin, obtainable by hydrolysis of their corresponding saponin molecules, are used by the pharmaceutical industry as raw materials for the synthesis of oral contraceptives and other classes of steroid drugs (Hardman, 1987).
Further study is therefore required in order to elucidate exact mechanisms on how various sapogenin structures influence protozoa cell structure, activity and metabolism.
Data obtained from previous in vivo studies using rats, mice and rabbits showed that saponins are not absorbed in the alimentary channel but hydrolyzed to their corresponding sapogenins (aglycone) and sugar, by enzymatic action in the gastrointestinal tract [5].
Sapogenins Quantification of Fresh and Fermented Juice of Fique (Furcraea gigantean) by High-Performance Liquid Chromatography (HPLC-PDA)
paniculatum that have in their structure one or two sugar chains attached by glycoside linkages to the aglycone, a non-saccharide portion of the molecule called sapogenin (Kohara et al.
saponaria extract had a high content of triterpene sapogenin with a triglycoside residue.
Simultaneous effect of calcium, magnesium, copper and cobalt ions on sapogenin steroids content in callus cultures of Agave amaniensis.
Diosgenin, a steroid sapogenin of the saponin dioscin, can undergo oxidation to produce a progesterone-like structure that has been used to synthesize human sex hormones and to treat conditions that are regulated by these hormones.
Aglycon sapogenin ginsenosides are not only safe, they have been found to both kill cancer cells and even normalize them.
Diosgenin, a steroidal sapogenin from the tubers of yams, is such an abundant source of vertebrate sex steroids that it remains a commercial source for hormones used in oral contraceptives (68).
Saponins (sapogenin glycosides) consist of an aglycone unit (sapogenin; a sterol or triterpene) linked to a sugar unit (glycone; one or more carbohydrate chains); they possess surface-active or detergent properties because the carbohydrate portion of the molecule is water-soluble whereas the sapogenin is fat-soluble (28).
In their natural range, these ferns are also used occasionally as foodstuffs, especially the tender shoots, although they need to be boiled to remove the high sapogenin content.