sanguinarine


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san·gui·na·rine

(sang'gwi-nā'rēn),
An alkaloid obtained from the bloodroot plant, Sanguinaria canadensis, used to treat and remove dental plaque.
Farlex Partner Medical Dictionary © Farlex 2012

sanguinarine

(săng′gwĭn-ă-rĭn)
A benzophenanthridine alkaloid available as an oral rinse and toothpaste. It is used to treat dental plaque and gingivitis.
Medical Dictionary, © 2009 Farlex and Partners

san·gui·na·rine

(sang'gwi-nār'ēn)
Alkaloid used to treat and remove dental plaque.
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive ?
Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.
Du, Ionic liquidliquid phase microextraction for the sensitive determination of sanguinarine and chelerythrine in Chinese herbal medicines and human urine, J.
reported that sanguinarine had preferential, concentration dependent tumour cytotoxicity when tested against the A431 epidermoid carcinoma cell line and normal human epidermal keratinocytes derived from foreskin.
Additionally, several alkaloids such as matrine and sanguinarine have been reported to possess anticancer activities [15].
chelerythrine, chelidonine, sanguinarine, isochelidonine), protoberberines (e.g.
in mice [143], and sanguinarine, an alkaloid isolated from Sanguinaria canadensis, had an [LD.sub.50] = 1658 mg/kg p.o.
The goal of this study was to investigate the antimicrobial activity of bee venom and its main component, melittin, alone or in two-drug and three-drug combinations with antibiotics (vancomycin, oxacillin, and amikacin) or antimicrobial plant secondary metabolites (carvacrol, benzyl isothiocyanate, the alkaloids sanguinarine and berberine) against drug-sensitive and antibiotic-resistant microbial pathogens.
IQA papaverine, sanguinarine, protoverine, and chelidonine are GI tract irritants and CNS stimulants (Ribeiro and Rodriguez de Lores Arnaiz 2000; Liu et al.
1) are the benzophenanthridine alkaloids (sanguinarine, chelerythrine and chelidonine) and protoberberines (berberine, coptisine).
aromadendrene,13-sitosterol-0-glucoside, and 13-carotene), and alkaloids (glaucine, harmine, and sanguinarine) were evaluated as potential P-gp inhibitors (transporter activity and expression level) in P-gp expressing Caco-2 and CEM/ADR5000 cancer cell lines.