safety profile


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

safety profile

The chemistry, pharmacology, therapeutic effects, and adverse effects of an administered drug or other substance.
See also: profile
References in periodicals archive ?
Although the European Union publishes a "black list" of airlines not reaching a certain level of safety requirements, there are real differences in terms of safety profiles among the other airlines.
Our strategy has been to capitalize on the product's unique safety profile by targeting indications above and beyond the existing US $1.
Safety Profile will also serve as the future foundation that will help customers certify their devices to additional IEC standards.
BL-1020 is an orally available GABA enhanced antipsychotic for the treatment of schizophrenia that was shown in preclinical studies to retain the efficacy of currently available typical and atypical antipsychotic drugs while achieving a much higher safety profile as evidenced by a lack of metabolic or extrapyramidal side effects.
Notably, no safety issues were raised and a recent post-marketing survey, citing worldwide treatment of more that 100 million patients, shows that the drug has a remarkable safety profile.
For example, ARQ 171, ARQ 501 and ARQ 197 may not demonstrate promising therapeutic effect; in addition, they may not demonstrate an appropriate safety profile in current or later stage or larger scale clinical trials as a result of known or as yet unanticipated side effects.
Having garnered such positive results in a variety of the traditional preclinical models for type 2 diabetes, combined with a good safety profile of the compound to date, gives us confidence as we enter HE3286 into clinical trials this year.
Xyrem has demonstrated an acceptable safety profile in narcoleptics with cataplexy when administered in nightly divided doses of 6 to 9 g with a recommended starting dose of 4.
Preliminary analysis of the safety profile of bevirimat in the first cohort indicated that bevirimat was generally safe and well tolerated.
Provision of the additional information will allow the FDA to determine the comparability of the new data submitted in November to that contained within the original Trexima NDA and to more fully assess the relative safety profile of Trexima.
PB has been well tolerated; its safety profile has generally been established due to its many years of clinical use in pediatrics for inherited urea cycle disorders.

Full browser ?