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1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.


A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.


A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: Hope this helps.

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References in periodicals archive ?
Talking to media persons, the advisor to PM said that concerted efforts have been made to open the border round the clock. He said it would disseminate message of peace in the world besides increasing trade activities with Afghanistan and central Asia.
The Director said that a Complaint Cell is working round the clock to receive various kinds of complaints and to resolve them swiftly.
"The 32-strong medical team is sparing no efforts to serve pilgrims, working as one team round the clock", said Bahrain Haj Medical Committee Chairman Dr.
Summary: New Delhi [India], July 18 (ANI): A Delhi court on Tuesday will make a decision over providing round-the-clock security to arms dealer Abhishek Verma in the 1984 riots, who had expressed willingness to undergo a polygraph test on the condition of round the clock security till the test takes place.
Intense infrastructural development activities coupled with a growing number of workers arriving in the country have led many eateries in Doha to remain open round the clock to cater to those working during the odd hours.
Available to all for free round the clock, the application can be accessed through smart phones, tablet PCs, computers and navigational devices in cars.
The official said the department will charge extra fees for issuing the commercial licences allowing round the clock work.
Alcohol could be served round the clock at hundreds of supermarket outlets once new laws come into force.
CELEBRITY survivor fans will be able to watch the new series of the show round the clock, producers revealed yesterday.
BUILDERS are working round the clock in a desperate bid to finish the pounds 32million Museum of Scotland so the Queen can open it on Monday.
Taimur Saleem said that Torkham is Pakistan's busiest international crossing with 10 thousand people and 1000 plus trucks crosses it every day, why should it only have been open for 8-10 hours a day, opening the border round the clock will be transformational.
Talking to media men here Thursday he said lying round the clock is job of selected Prime Minister.