rotenone


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Related to rotenone: pyrethrin

rotenone

 [ro´tĕ-nōn]
a poisonous compound from derris root and other roots; used as an insecticide.

ro·te·none

(rō'te-nōn),
The principal insecticidal component of derris root, Derris elliptica, D. malaccensis, and other D. species, and from Lonchocarpus nicou (family Leguminosae); used externally for the treatment of scabies and infestation with chiggers, and in veterinary medicine for follicular mange and infestation with lice, fleas, and ticks; an inhibitor of the respiratory chain.
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Effects of Rotenone Injection on Weight and General Motor Behavior.
The co-toxicity coefficient of rotenone and cinnamon oil mixture was analyzed by the Sun method (Wen et al.
The rotenone concentration and yield (dependent variables) were calculated based on the external standard method of RP-HPLC.
To identify whether BAG5 affects the protective property of DJ-1 in mitochondrial function, HEK293 cells expressing BAG5-Myc or BAG5-Myc with DJ-1-HA were treated with or without rotenone (100 nM) for 24 h.
This result was consistent with previously reported findings using radiotracer rotenone analogues.
For that reason, the aim of this work is to determine the lethal concentration ([LC.sub.50]) of the rotenone extracted from local plant species of Derris.
Effect of Rotenone Treatment on Renal Structural Change in Obstructed Kidneys.
Summary: Rotenone, one of traditional botanical insecticide, has been used more than one hundred years.
Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone. Arch Toxicol92, 25872606.
Rotenone (pesticide and mitochondrial complex I inhibitor) has been associated to induce toxicity in humans and as well as in animals.
Many mitochondrial poisons are known complex inhibitors (e.g., rotenone and antimycin A) and uncouplers (e.g., 2,4-dinitrophenol and carbonyl cyamide 4-(trifluoromethoxy)phenylhydrazone, or FCCP) of oxidative phosphorylation.