rosiglitazone


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Related to rosiglitazone: metformin, thiazolidinedione, troglitazone

rosiglitazone

 [ro-sig-lit´ah-zōn]
an antidiabetic agent that increases insulin sensitivity, used orally as the maleate salt in the treatment of type 2 diabetes mellitus.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

rosiglitazone

(rō′sĭ-glĭt′ə-zōn′)
n.
A thiazolidinedione drug, C18H19N3O3S, used in its maleate form to treat type 2 diabetes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

rosiglitazone

Avandia® Therapeutics A thiazolidinedione used in Pts with type 2 DM to ↑ the efficiency with which the body uses insulin Adverse effects Flu-like Sx, headache, weight gain Contraindications CHF
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

rosiglitazone

A THIAZOLIDINEDIONE drug used to control HYPERGLYCAEMIA in patients with Type 2 DIABETES. It reduces insulin resistance and has been found capable of restoring normoglycaemia and reducing the incidence of Type 2 diabetes in patients with impaired glucose rolerance or impaired fasting glucose levels, or both.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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References in periodicals archive ?
Mefformin may take as long as 6 months to exert an optimal effect on ovulation, and rosiglitazone 3 to 4 months to improve insulin sensitivity
Q: Is rosiglitazone superior to metformin for women with PCOS?
A total of 208 children aged 8-17 years with type 2 diabetes entered a 4-week run-in period, and 200 were randomized to either rosiglitazone 2 mg twice daily or metformin 500 mg twice daily.
Two oral agents benefit type 2 diabetes patients: glimepiride, rosiglitazone look good
Rosiglitazone in the treatment of HAART-associated lipodystrophy (HAL): A randomized, double-blind, placebo-controlled trial.
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In differentiating rosiglitazone from other agents, Harold E.
New Type 2 diabetes drug takes aim at insulin resistance
Neural stem cells derived from the spinal cord were divided into three groups, namely, the rosiglitazone group, treated with rosiglitazone (1 [micro]mol/L in DMSO [Abcam, ab142179]), the G3335 group, treated with G3335 (PPAR-[gamma]antagonist 0.1 [micro]mol/L) and DMSO, and the vehicle group, treated with DMSO.
Combined Rosiglitazone and Forskolin Have Neuroprotective Effects in SD Rats after Spinal Cord Injury
Rosiglitazone was purchased from Sigma-Aldrich; PPAR[gamma] antagonist GW9662 and RXR antagonist HX531 were purchased from Tocris Bioscience.
Expression of GPR43 in Brown Adipogenesis Is Enhanced by Rosiglitazone and Controlled by PPAR[gamma]/RXR Heterodimerization
Rosiglitazone treatment has been found to improve hypoadiponectinemia in patients with nonalcoholic steatohepatitis [19].
Rosiglitazone Elicits an Adiponectin-Mediated Insulin-Sensitizing Action at the Adipose Tissue-Liver Axis in Otsuka Long-Evans Tokushima Fatty Rats
PPARy agonist drug Rosiglitazone was used (Sigma-Aldrich) and rosiglitazone inhibitor, GW-9662 (Sigma-Aldrich).
Rosiglitazone Role in the Expression of KLF6 Caco-2 Colon Cancer Cells/Rol de Rosiglitazona en la Expresion de KLF6 en Celulas Caco-2 de Cancer de Colon
To assess whether activation of PPAR-[gamma] prevents sepsis-induced cardiac dysfunction, PPAR-[gamma] agonist rosiglitazone or antagonist T007 was injected intravenously 1 hour prior to CLP surgery.
PPAR-[gamma] Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis
Following a week of environmental habituation, the rats were randomly divided into control (n = 8), NASH model (n = 8), salidroside treatment (n = 8), and rosiglitazone treatment (n = 8) groups.
Salidroside Modulates Insulin Signaling in a Rat Model of Nonalcoholic Steatohepatitis
Objective: To evaluate the effect of pomegranate peel extract with or without rosiglitazone on plasma glucose and lipid profile in insulin resistant diabetic rats.
EFFECT OF POMEGRANATE PEEL ALONE AND IN COMBINATION WITH ROSIGLITAZONE ON HYPERGLYCEMIA AND DYSLIPIDEMIA IN TYPE 2 DIABETES MELLITUS

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