This novel test detects trichothecene mycotoxins--including satratoxin (G & H), roridin A, roridin L-2, verrucarol and verrucarin A produced by Stachybotrys and other toxic molds.
The ELISA has a quantitation range for roridin A of 0.
The complex trichothecenes, satratoxin and roridin, produced by Stachybotrys chartarum, were found in minute quantities.
Because there are currently no useful biological monitoring techniques to assess exposure to mycotoxins, we conducted a pilot serologic evaluation using a test under development to identify specific IgG and IgM antibodies to roridin (a tricothecene mycotoxin known to be produced by several different fungi including Stachybotrys species).
Although this laboratory testing did yield evidence that individuals may make specific IgG antibodies to roridin, the source of the exposure that led to this response cannot be determined from our data.
Enzyme immunoassay for the macrocyclic trichothecene roridin A: production, properties, and use of rabbit antibodies.