Cholinesterase inhibitors are a class of drugs that include donepezil, rivastigmine
, and galantamine.
Pharmacokinetics and bioavailability of the novel rivastigmine
transdermal patch versus rivastigmine
oral solution in healthy elderly subjects.
He went on to note that donepezil "is more likely to give you diarrhea than rivastigmine
is, and the rivastigmine
patch will give you a rash in 5%-10% of patients.
A very common treatment for Alzheimer's disease is an acetylcholine esterase inhibitor such as galantamine (Reminyl), rivastigmine
(Exelon) and donepezil (Aricept).
The drugs in the acetylcholinesterase class are tacrine (Cognex), donepezil (Aricept), rivastigmine
(Exelon), and galantamine (Razadyne).
gt;What it is: In July, the Food and Drug Administration approved a patch version of rivastigmine
, also know as Exelon, used in the treatment of mild to moderate cases of Alzheimer's and mild to moderate dementia associated with Parkinson's.
Randomized, placebo-controlled trials of donepezil, rivastigmine
and galantamine have demonstrated that these drugs have clinically meaningful responses in AD patients.
(Exelon)--Believed to block an enzyme that contributes to brain damage during the later stages of Alzheimer's disease, although no clinical studies yet support that view.
Four of the drugs--tacrine (Cognex), donepezil (Aricept), rivastigmine
(Exelon) and galantamine (Reminyl)--are known as cholinesterase inhibitors.
Approved cholinesterase inhibitors--including rivastigmine
(Exelon), donepezil (Aricept), and galantamine (Reminyl)--work by slowing the body's breakdown of a chemical that plays a role in memory.
These therapies include the acetylcholinesterase inhibitors (AChEIs) donepezil (Eisai/Pfizer's Aricept, generics), galantamine (Ortho-McNeil Neurologic's Razadyne, Razadyne ER, generics), and rivastigmine
(Novartis's Exelon, generics, and the Exelon patch) as well as the NMDA receptor antagonist memantine (Forest Laboratories' Namenda).
By way of derogation for lots 40 Metoprolol (succinate) - C07AB02 and 51 Rivastigmine
(External) - N06DA03 as contract end each of 31/10/2017.