rimantadine

Related to rimantadine: rimantadine HCl

rimantadine

[ri-man´tah-dēn]

an antiviral agent used in prophylaxis and treatment of influenza A.

rimantadine

Flumadine^® An antiviral analogue of amantadine and ±75% effective in preventing influenza A during community epidemics; it is partially effective as therapy and post-exposure prophylaxis for influenza A, as drug-resistant strains rapidly appear. See Canyon region.

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References in periodicals archive ?

Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine. Curr.

In vitro anti-viral effect of [beta]-santalol against influenza viral replication

Of the anti influenza virus drugs available, the M2 inhibitors have a longer history of use than NA inhibitors and include amantadine and rimantadine. Amantadine's therapeutic antiviral spectrum is limited to influenza A virus.

Comparative Efficacy of Various Antiviral Agents against Avian Influenza Virus (Type H7N3/Pakistan/2003)

Treatment of influenza: the therapeutic efficacy of rimantadine HCI in naturally occurring influenza A2 outbreak.

Effect of amantadine on serumic levels of creatinine in native poultry

Influenza Treatment with Antiviral Agents Dosing Recommendations * Due to seasonal influenza A (H1N1) resistance to oseltamivir, patients with suspected seasonal influenza A (H1N1) virus infection should be treated with zanamivir or alternatively with a combination of oseltamivir and an adamantane if zanamivir use is contraindicated (rimantadine is preferred over amantadine because of an increased risk of adverse events associated with amantadine).

Pediatric influenza

The recommended alternative to zanamivir in patients with laboratory evidence of influenza A, a negative test result, or no testing is the combination of oseltamivir plus rimantadine (Flumadine).

Antiviral therapies for the upcoming flu season clarified

The data also show that virus is resistant to amantadine and rimantadine but the organism continues to remain susceptible to oseltamivir and zanamivir.

Influenza A (H1N1): responding to a pandemic threat

The CDC recommendation advised doctors to combine Tamiflu with rimantadine (an older antiviral) or to substitute Tamiflu with Relenza (zanamivir), an antiviral that arrived on the market about 10 years ago.

Despite a mild flu season, questions surface about Tamiflu

The researchers examined the response of HCV to a panel of compounds including the well-known anti-viral drug, rimantadine, which targets a similar protein in the flu virus.

Combination therapies may be effective against hepatitis C virus

However, four drugs have been approved to treat people who get the flu: amamadine (Symmetrel), rimantadine (Flumadine), zanamivir (Relenza), and oseltamivir (Tamiflu).

Shots for safety

This drug and its congener, rimantadine (not available in South Africa), specifically inhibit the replication of influenza A viruses (they are ineffective against influenza B viruses) in low concentrations of about 0.03 - 1.0 [micro]g/ml.

Role of antivirals in influenza

FDA said beginning this summer, it is proposing to ban veterinarians from prescribing off-label, nonhuman uses of Tamiflu, amantadine and rimantadine. The United States has been stockpiling drugs for a possible avianflu outbreak in humans.

U.S. poultry companies develop avian flu marketing strategies

Tom Jefferson and his colleagues from the Cochrane Vaccines Field examined evidence from trials on the efficacy of all four flu drugs: Tamiflu, Relenza, Amantadine, and Rimantadine. They strongly warn against relying on drugs to stamp out a potential avian flu pandemic and believe complacency will deter the use of public-health measures, such as hygiene and isolation, to stop the spread of infection.