rifamycin


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Related to rifamycin: Rifaximin

rifamycin

 [rif″ah-mi´sin]
any of a family of antibiotics biosynthesized by a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria. The five components are designated A, B, C, D, and E; rifamycins O, S, and SV are derivatives of the B component, and AG and X are derivatives of the O component. Used for the initial treatment and retreatment of pulmonary tuberculosis and for prevention of meningoccal infections in close contacts of patients with Neisseria meningitidis infections.

rifamycin

/rif·a·my·cin/ (rif″ah-mi´sin) any of a family of antibiotics biosynthesized by a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria, including gram-positive cocci, some gram-negative bacilli, and Mycobacterium tuberculosis and certain other mycobacteria; used for the treatment of tuberculosis and the prophylaxis of meningococcal infections.

rifamycin

(rĭf′ə-mī′sĭn)
n.
Any of a group of antibiotics originally isolated from a strain of the soil microorganism Streptomyces mediterranei, used in the United States to treat tuberculosis and prevent meningococcal infections, and used in other countries to treat leprosy and other bacterial diseases.

rifamycin

[rif′ah-mi′sin]
any of a family of antibiotics biosynthesized from a strain of Streptomyces mediterranei, effective against a broad spectrum of bacteria. The five components are designated A, B, C, D, and E; rifamycins O, S, and SV are derivatives of the B component, and AG and X are derivatives of the O component. It is used for the initial treatment and retreatment of pulmonary tuberculosis and for prevention of meningococcal infections in close contacts of patients with Neisseria meningitidis infections.

rifamycin

a family of antibiotics produced in cultures of Streptomyces mediterranei. Effective against gram-positive cocci and gram-negative bacilli and mycobacteria including Mycobacterium tuberculosis.
References in periodicals archive ?
Priftin is contraindicated in patients with a history of hypersensitivity to rifamycins.
Rifamycin SV MMX: In September 2012, Santarus announced that patients treated with rifamycin SV MMX demonstrated statistically significant improvement in reducing time to last unformed stool in patients with travelers' diarrhea, the primary endpoint of a Phase III clinical study to evaluate the safety and efficacy of rifamycin SV MMX versus placebo.
By using a specialized analytical technique called ion mobility spectrometry-mass spectrometry (IMS-MS), the researchers were able to see at what stage of the process Rifamycin SV prevented amyloid fibril formation.
One recent report of clofazimine combined with a macrolide and ethambutol without the use of any rifamycin showed successful treatment with an 87% sputum conversion rate after 10 months of therapy.
One of those was rifabutin, a chemical modification of rifamycin.
RIF is a semisynthetic derivative of rifamycin that is used as a first-line TB drug.
Relapse with rifamycin mono-resistant tuberculosis in HIV-infected patients treated with supervised once-weekly rifapentine and isoniazid.
Both fluoroquinolones have pharmacokinetics amenable to weekly dosing, as does rifapentine, a long-acting rifamycin developed in the 1990s.
For MAC pulmonary disease in HIV-seronegative patients, the 1997 ATS consensus statement recommended empiric treatment with daily azithromycin or clarithromycin, ethambutol, and a rifamycin (rifampin or rifabutin).
Santarus also has a diverse development pipeline with three late-stage product candidates in Phase III clinical programs: ULTESA(TM) (budesonide MMX) for induction of remission of active ulcerative colitis, RHUCIN (recombinant human C1 inhibitor) for treatment of acute attacks of hereditary angioedema and rifamycin SV MMX for treatment of travelers' diarrhea.
Acquired rifamycin resistance with twice-weekly treatment of HIV-related tuberculosis.
In addition, 2 weeks of daily treatment with rifaximin, an antibiotic derived from rifamycin, had a minimal effect on native, enteric flora, Dr.