ricin

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Related to ricin toxin: anthrax, Anthrax toxin, Botulism toxin

ricin

 [ri´sin]
a phytotoxin in the seeds of the castor oil plant (Ricinus communis), inhalation or ingestion of which causes intoxication, producing superficial inflammation of the respiratory mucosa with hemorrhages into the lungs, or edema of the gastrointestinal tract with hemorrhages.

ri·cin

(rī'sin, ris'in),
A highly toxic lectin and hemagglutin that occurs in castor beans (the seeds of the castor oil plant, Ricinus communis; if ingested, acts as a violent irritant with possibly fatal results, on the respiratory and gastrointestinal mucosa; an N-glycosidase that acts on the GOS subunit of rRNA, halting protein translation.

ricin

/ri·cin/ (ri´sin) a phytotoxin in the seeds of the castor oil plant (Ricinus communis), used in the synthesis of immunotoxins.

ricin

[rī′sin]
a poison made from waste produced in processing castor beans. It can take the form of a powder, mist, or pellet or can be dissolved in water or weak acid and can be used as a poison by ingestion, inhalation, or injection. As little as 500 micrograms can be a fatal dose. It cannot be spread by person-to-person contact. Poisoning is treated by minimizing exposure and by supportive care. There is no antidote. Also called ricinine. See also ribosome-inactivating protein.

ricin

Toxicology A toxic vegetable poison from the castor bean plant–Ricinus communis which causes agglutination and fulminant hemolysis at very high dilutions–1/106 Clinical Abdominal pain, nausea, cramps, convulsions, dehydration, hemolysis, cyanosis, renal failure–oliguria, hematuria, circulatory collapse. See Magic bullet.

ri·cin

(rī'sin)
Toxin derived from castor beans that causes inflammation of the gastrointestinal mucosa and the respiratory tract.
[L. ricinus, castor oil plant]

ricin

A highly poisonous substance found in the castor oil bean Ricinis communis .

ri·cin

(rī'sin)
A highly toxic lectin and hemagglutinin that occurs in castor beans (the seeds of the castor oil plant, Ricinus communis); if ingested, acts as a violent irritant with possibly fatal results, on the respiratory and gastrointestinal mucosa.
[L. ricinus, castor oil plant]

ricin

phytotoxin (combining lectin, toxalbumin, hemagglutinin) in the seeds of the castor oil plant (Ricinus communis), inhalation or ingestion of which causes intoxication, producing superficial inflammation of the respiratory mucosa with hemorrhages into the lungs, or edema of the gastrointestinal tract with hemorrhages.
References in periodicals archive ?
RiVax, Soligenix's proprietary heat stable recombinant subunit vaccine developed to protect against exposure to ricin toxin, contains a genetically altered version of a Ricin Toxin A chain containing two mutations that inactivate the toxicity of the ricin molecule.
Ricin toxin is a potential bioterror threat that is toxic in small doses, is easy to obtain, and has the ability to be aerosolized.
Because vaccine efficacy for exposure of humans to ricin toxin can only be tested in animals, the FDA has established a two animal rule.
In January 2006, AVI gained approval for an $11 million allocation as part of the Defense Appropriations Act to develop therapeutic agents against Ebola, Marburg and dengue viruses, as well as countermeasures for anthrax exposure and antidotes for ricin toxin.
E[acute accent]Using the company's dual stage filter architecture, Nephros has developed a new proprietary water filtration device that is designed to remove a broad range of bacteria, viral agents and toxic substances, including salmonella, hepatitis, HIV, Ebola virus, ricin toxin, legionella, fungi and e-coli.
In January, DOR announced positive results of its Phase I clinical trial of RiVax(TM), which represented the first time a ricin toxin vaccine had ever been clinically tested in humans.
In January, DOR and Cambrex BioSciences announced completion of an agreement for process development and large scale production of RiVax(TM), DOR's vaccine against ricin toxin.
According to Israel, Cordesman wrote, "Syria weaponized botulinum and ricin toxins in the early 1990s, and probably anthrax.