DHFR: dihydrofolate reductase; TYMS: thymidylate synthase; ATIC: aminoimidazole carboxamide ribonucleotide (AICAR) transformylase; FAICAR: 5-formamidoimidazole-4-carboxamide ribotide
; IMP: inosine monophosphate; AMP: adenosine monophosphate; AMPK 5' adenosine monophosphate-activated protein kinase; ADA adenosine deaminase; 5'-NT: 5'-nucleotidase; -: inhibition; + activation.
It catalyses the conversion of succinylaminoimidazole carboxamide ribotide
(SAICAR) to aminoimidazole carboxamide ribotide
(AICAR), as well as, the formation of adenosine monophosphate (AMP) from adenylosuccinate in the purine nucleotide cycle (Kmoch et al., 2000; Toth and Yeates, 2000).
Inhibition of 5-aminoimidazole-4-carboxamide ribotide
transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide
For example, flavors need not employ hydrolyzed vegetable protein, monosodium glutamate, ribotide
or autolyzed yeast extract.
This concerns the conversion of SAICA-ribotide into aminoimidazole carboxamide ribotide
and of adenylosuccinate into AMP (Fig.
Stop by for a taste of the South enhanced with Ribotide
. Also, vitamin C fortifies two refreshing tropical beverages.