riboswitches

riboswitches

Short segments of RNA that can act a on/off switches for genes.
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In contrast, in bacteria, most studies regarding post-transcriptional regulation have been mainly focused on specific non-coding RNAs and 5 UTRs, which often carry riboswitches or thermosensors.
It is very likely no one would have solved the mystery of fluoride riboswitches for several more decades, if we had not been lucky enough to receive a contaminated chemical sample spiked with fluoride.
Unlike other known riboswitches, which have relatively limited functions, this one acts as a sensor for the basic molecular fuel that powers all living cells and controls many genes.
22 online issue of the journal Science Express, the researchers report that sections of RNA messages called riboswitches -- which control the expression of genes -- detect the build-up of fluoride and activate the defenses of bacteria, including those that contribute to tooth decay.
The section on non-coding RNA includes discussions of transfer RNAs, small nucleolar RNAs, small non-coding RNAs and the mechanisms of gene silencing, RNA editing, and riboswitches and RAN sensors.
They present 26 papers exploring these two primordial and present-day RNA Worlds through discussions of the role of RNA in the first life forms and the appearance of cells, characteristics of riboswitches and ribozomes, protein synthesis on ribosomes, recent discoveries concerning RNA regulated gene expression, and tools and methodologies for RNA science.
We are confident their expertise, insights and commitment to high quality medicinal chemistry, coupled with our propriety and leading position on Riboswitches, will continue to deliver value in important new medicines.
BioRelix is building a portfolio of anti-infective products based on novel patented RNA targets, termed RiboSwitches, which were identified in the laboratory of BioRelix co-founder, Ronald Breaker Ph.
The researchers are now developing riboswitches for particular applications, Gallivan says.
Scientists at Yale University are concentrating on riboswitches.
Any water with ionic charges, no matter how clean, alkaline, or well-filtered it is, can turn off the hepatocyte production of bile as well as the riboswitches of over 5 million genes in the microbiome.
In the new study, researchers at Yale University report that sections of RNA messages called riboswitches, which control the expression of genes, detect the build-up of fluoride and activate the defences of bacteria, including those that contribute to tooth decay.