ribosome

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ribosome

 [ri´bo-sōm]
any of the intracellular ribonucleoprotein organelles concerned with protein synthesis, found either bound to cell membranes or free in the cytoplasm. They may occur singly or in clusters (polyribosomes). The genetic code is translated when ribosomes attach to messenger RNA.

ri·bo·some

(rī'bō-sōm),
A granule of ribonucleoprotein, 120-200 Ǻ in diameter, that is the site of protein synthesis from aminoacyl-tRNAs as directed by mRNAs.
Synonym(s): Palade granule

ribosome

(rī′bə-sōm′)
n.
A structure composed of RNA and protein, present in large numbers in the cytoplasm of living cells and serving as the site for assembly of polypeptides encoded by messenger RNA.

ri′bo·so′mal (-sō′məl) adj.

ri·bo·some

(rī'bŏ-sōm)
A granule of ribonucleoprotein, 120-150 Å in diameter, which is the site of protein synthesis from aminoacyl-tRNAs as directed by mRNAs.

ribosome

A spherical cell ORGANELLE made of RNA and protein which is the site of protein synthesis in the cell by linking amino acids into chains. Ribosomes may be free or may be attached to the endoplasmic reticulum. During translation, ribosomes attach to MESSENGER RNA molecules and travel along them, synthesizing polypeptides as they go.

ribosome

a small particle (not an ORGANELLE) found in the cytoplasm of all cells, composed of protein and RIBOSOMAL RNA. Each ribosome is composed of two subunits of different sizes which sediment at different rates during centrifugation (see ULTRACENTRIFUGE). PROKARYOTES have ribosome with 70 S size and mass; EUKARYOTES have larger ribosomes with 80 S size and mass. Ribosomes bind to the 5′ end of MESSENGER RNA (see POLYNUCLEOTIDE CHAIN) and travel towards the 3′ end, with TRANSLATION and POLYPEPTIDE synthesis occurring as they go along. Frequently several ribosomes are attached to one piece of mRNA, forming a POLYRIBOSOME.

Palade,

George Emil, Romanian-U.S. cell biologist and Nobel laureate, 1912–.
Palade granule - a granule of ribonucleoprotein, the site of protein synthesis from aminoacyl-tRNAs as directed by mRNAs. Synonym(s): ribosome
Weibel-Palade bodies - see under Weibel
References in periodicals archive ?
Tannins remarkably downregulated 44 ribosomal proteins, which is the highest number of ribosomal genes downregulated compared to other previous studies.
Ribosomal DNA plays a critical role in healthy cells and cancer cells alike.
We also found that treatment with hyaluromycin resulted in decreased phosphorylation of ribosomal protein S6, a mediator of PI3K/Akt/mTOR pathway [20].
According to these results, levels of ribosomal protein, transcription factors, and translation factors were found about the same level at both stages.
Our findings reinforce previous reports [25,26] on the occurrence of dysregulated expression among a subset of ribosomal protein genes in NPC.
Further, ribosomal 5.8S gene is generally employed with markers ITS1 and ITS2, which together form the complete region of the transcribed internal spacer (Jousson, Bartoli, Zaninetti, & Pawlowski, 1998).
Altered ribosomal function has been seen in people infected with Epstein-Barr virus, which is strongly associated with chronic fatigue syndrome.
The exact ribosomal function of specific ribosomal proteins is largely unknown (Wool et al.
epidermidis linezolid resistance on various continents have been low and are associated with mutations in the central loop of 23S rRNA V domain or ribosomal proteins (L3, L4, and L22) and with acquisition of the cfr gene, which codifies for ribosomal methyltransferase (1-3).
This notably reduces sequencing reads derived from unwanted transcripts, such as ribosomal RNA, globin and protein-coding RNAs, including housekeeping genes, which leads to cost reduction.
They came up with three ribosomal protein candidates - s11, s15 and s27.