rhodopsin


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Related to rhodopsin: Rhodopsin kinase, photopsin

rhodopsin

 [ro-dop´sin]
visual purple: a photosensitive purple-red chromoprotein in the retinal rods that is bleached to visual yellow (all-transretinal) by light, thereby stimulating retinal sensory endings. Lack of rhodopsin results in night blindness. Vitamin A is the primary source of rhodopsin.

rho·dop·sin

(rō-dop'sin), [MIM*180380]
A purplish-red thermolabile protein, MW about 40,000, found in the external segments of the rods of the retina; consists of opsin combined with 11-cis retinal; it is bleached by the action of light, which converts it to opsin and all-trans-retinal, and is restored in the dark by rhodogenesis; the dominant protein in the plasma membrane of rod cells.
Synonym(s): visual purple

rhodopsin

/rho·dop·sin/ (ro-dop´sin) visual purple; a photosensitive purple-red chromoprotein in the retinal rods that is bleached to visual yellow (all-trans retinal) by light, thereby stimulating retinal sensory endings.

rhodopsin

(rō-dŏp′sĭn)
n.
Any of a class of reddish, light-sensitive pigments found in the retinal rods of the eyes of terrestrial and marine vertebrates, consisting of opsin and retinal. Also called visual purple.

rhodopsin

[rōdop′sin]
Etymology: Gk, rhodon, rose, opsis, vision
the purple pigmented compound in the rods of the retina, formed by a protein, opsin, and a derivative of vitamin A, retinal. Rhodopsin gives the outer segments of the rods a purple color and adapts the eye to low-density light. The compound breaks down when struck by light, and this chemical change triggers the conduction of nerve impulses. Brief periods of darkness allow the opsin and the retinal to reconstitute the rhodopsin, which accounts for the short delay a person experiences in adapting to sudden or drastic changes in lighting, as when moving out of bright sunlight into a darkened room or from darkness into bright light. Closing the eyes is a natural reflex that allows reconstitution of rhodopsin. Compare iodopsin. See also visual purple.

rho·dop·sin

(rō-dop'sin)
A red thermolabile protein found in the rods of the retina; it is bleached by the action of light, which converts it to opsin and all-trans-retinal, and is restored in the dark by rhodogenesis; the dominant protein in the plasma membrane of rod cells.
Synonym(s): visual purple.

rhodopsin

The retinal rod photoreceptor pigment. Also known as visual purple.

rhodopsin

a photochemical pigment found in the rods of the retina of the vertebrate eye. When bleached by absorbed light, rhodopsin dissociates into its two components - a pigment called RETINAL and a protein called OPSIN. This dissociation ultimately triggers an action potential and the production of nerve impulses in the ganglion cells leading to the optic nerve. Lack of rhodopsin causes night blindness.

rhodopsin 

Visual pigment contained in the outer segments of the rod cells of the retina and involved in scotopic vision. When light stimulates the retina, the chromophore of the pigment molecule '11-cis' retinal (which is vitamin A aldehyde) isomerizes to 'all-trans' retinal. This leads to other chemical transformations which carry on even in the absence of light. The first stage is prelumirhodopsin, then lumirhodopsin and finally metarhodopsin (of which there are two types). This last transformation may lead to the breakdown of the molecule into retinal and opsin. The molecule is regenerated by recombining retinal and opsin with some enzymes. The absorption spectrum of rhodopsin has a maximum around 498 nm. The isomerization from '11-cis' to 'all-trans' also gives rise to the process of transduction in which the membrane potential covering the pigment molecules in the outer segment changes towards a hyperpolarization of the cell. This is the first step in the nervous response to a light stimulation of the retina. Syn. visual purple (not used any more); erythropsin. See dark adaptation; bleaching; receptor potential; absorption spectrum; transduction.

rho·dop·sin

(rō-dop'sin) [MIM*180380]
A red thermolabile protein found in the rods of the retina.
Synonym(s): visual purple.

rhodopsin (rōdop´sin),

n a purple light-receptive pigment found in the retina and consisting of opsin and retinal. Rhodopsin helps the eye adjust to drastic changes in environmental lighting.

rhodopsin

visual purple: a photosensitive purple-red chromoprotein in the retinal rods that is bleached to visual yellow (all-trans-retinal) by light, thereby stimulating retinal sensory endings. Lack of rhodopsin results in night blindness. Vitamin A is the primary source of rhodopsin.
References in periodicals archive ?
Rhodopsin is a photoreceptor pigment of the retina which initiates vision upon capturing of a photon by the chromophore 11-cis retinal, a retinal iso- mer.
In past, it was observed that the rate-limited supply of 11-cis-retinal from the retina pigment epithelium (RPE) to the outer side of the photoreceptors has direct effects on the rhodopsin cycle [27].
The gua nine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni.
The most relevant structure elucidated has been that of rhodopsin (67), the impact of which has been reviewed (68).
While conceding that anatomical eye evolution can be accounted for by gradual evolution, the author concludes that the sequence of reactions required to convert absorption of photons by rhodopsin into a nervous impulse and restore rhodopsin is an example of irreducible complexity.
Women were considered as case subjects when they answered "no" to question 1 and "yes" to question 2 and/or 3, since this ocular symptom reflects the functional role of vitamin A in the formation of rhodopsin (21,22).
These antioxidant compounds, have been described as accelerating the resynthesis of rhodopsin, a chromoprotein in retinal rods that stimulates the retinal sensory endings as it is formed and degraded (Soc.
These antioxidant compounds, which have been studied for decades, have been described as accelerating the resynthesis of rhodopsin, a chromoprotein in retinal rods that stimulates the retinal sensory endings as it is formed and degraded (Soc.
Protein Secondary Structures and Homology by Neural Networks: The Alpha-Helices in Rhodopsin.
These reactions produce a chemical called activated rhodopsin, which creates electrical impulses in the optic nerve.