1972), [beta]-D-glucuronidase (Kawai and Anno 1971) and rhodanese (Sorbo 1955).
5) were found to be elevated while the level of rhodanese (Fig.
An enzyme present in high concentration in normal cells but very low in cancer cells is the enzyme rhodanese
or sulfur transferase.
In the body cyanide is detoxified by the enzyme rhodanese
, forming thiocyanate, which is excreted in the urine.
Cyanide is detoxified via rhodanese
and b-Mercaptopyruvate-cyanide-sulfur transferase to thiocyanate.
Monte Carlo molecular modeling approaches indicate that a mushroom-like conformation for dPJ9 yields theoretical scattering data that agrees well with the experimental data, similar to results obtained for rhodanese
Detoxification can also include administration of thiosulfate, which is incorporated into thiocyanate by rhodanese
(a mitochondrial transsulfurase enzyme) and excreted in the urine.
Indeed, a review of the history and evolution of shipping policies, dating back to the period of the early eastern Mediterranean civilizations of the Phoenicians, Greeks, Rhodanese
, and Romans, and the later expansionist policies of western European nations such as those of the Dutch, British, and French, lend credence to the extraordinary significance attached to shipping policies.
inside the cells is catalyzed by enzymes which are highly activated by rhodanese
that in turn activates C[N.
The conversion of cyanide to thiocyanate in the body is catalyzed by the enzyme rhodanese
and uses sulfur that originates from the essential amino acids methionine and cystine, which further reduces the essential amino acid content of a diet that may already be marginal in protein intake (7,10).
Comparative studies on the distribution of rhodanese
in different tissues of domestic animals.
However, in ruminants, HCN can be rapidly detoxified by rhodanese
and [beta]-mercaptopyruvate sulfurtransferase (Martensson and Sorbo, 1978; Frankenberg, 1980) by rumen microbes (Majak and Cheng, 1984) and animal tissues (rumen wall, liver, kidney and red blood cell) (Aminlari and Gilapour, 1991; Aminlari et al.