Tissue cultures from this specimen were negative for fungi and acid-fast bacteria, however, they had positive results for gram-negative bacilli; 16s ribosomal RNA (rRNA) gene sequencing identified the organism as K rhinoscleromatis, and a diagnosis of tracheal rhinoscleroma
) a histologic, immunohisto chemical study with bacteriologic correlates.
Non-neoplastic and neoplastic causes of focal tracheal narrowing Non-neoplastic Neoplastic Post intubation Carcinoid Post infectious (TB, Adenoid cystic carcinoma tracheal papillomatosis, rhinoscleroma
) Extrinsic compression Mucoepidermoid carcinoma Pleomorphic adenoma Squamous cell carcinoma A useful mnemonic to remember the neoplastic causes of focal tracheal narrowing is "CAMPS."
Early diagnosis of ozena and rhinoscleroma
through a fast and specific molecular method with high discriminatory power at subspecies level might contribute to a rapid therapeutic formulation and thus leading to improvement ofpatient prognosis, avoiding destructive consequences and sequelae on the respiratory mucosa.
Hard palate in 10(8.1%) cases which included leukoplakia (1), pseudoepitheliomatous hyperplasia (1), pleomorphic adenoma (1), chronic inflammation (3), rhinoscleroma
(1), rhinosporidiosis (1), actinomycosis (1), pyogenic granuloma (1).
Nasal endoscopy was done, biopsy was sent for histopathological examination which showed fragments of soft tissue showing several inflammatory cells and large histocytes with foamy cytoplasm without any evidence of infection, consistent with rhinoscleroma
The clinical and microscopic manifestation of SHML should be differentiated from malignant lymphoreticular neoplasias, such as Hodgkin's disease and monocytic leukemia, histiocytosis, rhinoscleroma
, tuberculosis, juvenile xanthogranuloma, dermatofibromas, and eosinophilic granuloma, among others.
Classification of nasal granulomas Infectious Mycobacterial: Tuberculosis (human, bovine, or avian); atypical tuberculo- sis; leprosy Bacterial: Rhinoscleroma
Treponemal: Syphilis; yaws Fungal: Mucormycosis; aspergillosis; blastomycosis; histoplasmosis; coccidiomycosis; rhinosporidiosis Parasitic: Leishmaniasis Noninfectious Wegener's granulomatosis Sarcoidosis Inclusion granuloma (silicosis; berylliosis) Foreign-body retention Malignant Lethal midline granuloma Nonspecific
cases were 3 (8.5%), presented with nasal obstruction, foul smelling nasal discharge and crusting.
The differential diagnoses of nasal tuberculosis include other granulomatous diseases of the nose (e.g., Wegener' s granulomatosis and lethal midline granulomatosis), specific granulomas (e.g., syphilis, rhinoscleroma
, and rhinosporidiosis), and fungal granulomas (e.g., blastomycosis, histoplasmosis, and coccidioidomycosis).
is an unusual chronic granulomatous disease of the upper airways that is caused by Klebsiella rhinoscleromatis.
(1 case-2.44%) was reported in a twenty- two year old male, who presented with a mass in the right nasal cavity.