rheumatoid nodule

rheumatoid nodule

A mass in tendons, tendon sheaths, periarticular tissue, serous membranes–pleural, pericardium, meninges, cardiac valves, kidneys, lung parenchyma, skin, spleen, synovium, vessels, viscera, in 20% of Pts with rheumatoid arthritis DiffDx Similar nodules occur in SLE, rheumatic fever. See Rheumatoid arthritis.
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The pathological findings in the majority of the MIAN case reports that we reviewed showed the classic findings of the classic rheumatoid nodule.
11 Seropositivity is associated with rheumatoid nodule formation in approximately 25% of patients as the most common extra- articular manifestation of RA12 and the presence of anti-CCP predicts more aggressive disease13 but seronegative RA can be aggressive as well.
Relapse of cutaneous leishmaniasis in a patient with an infected subcutaneous rheumatoid nodule.
In this study, extra-articular feature in rheumatoid arthritis group noted were as follows: Rheumatoid nodule 3(8%), interstitial lung fibrosis 1(2%), ischemic heart disease 2(4%), osteoporosis 3(8%).
Subcutaneous granuloma annulare should be differentiated from rheumatoid nodule, sarcoidosis, infections and tumours.
Table 1: Differential diagnosis: Solitary pulmonary nodule Infectious Granuloma Mycobacteria Fungus Sarcoidosis (rare) Organizing pneumonia Lung abscess (or septic embolus) Round pneumonia Fungal pneumonia Neoplastic Benign Hamartoma Inflammatory (myofibroblastic) pseudotumor Sclerosing hemangioma Granular cell tumor Malignant Bronchogenic carcinoma Solitary metastasis Carcinoid/atypical carcinoid tumor Vascular Arteriovenous malformation Pulmonary infarct Hematoma Pulmonary artery aneurysm Lymphatic Intrapulmonary lymph node Lymphoma Congenital Bronchogenic cyst Inflammatory Rheumatoid nodule Wegener's granulomatosis Airway Mucoid impaction (bronchiectasis) Miscellaneous Rounded atelectasis Amyloidosis
Histologic examination revealed an intramural lesion composed entirely of spindle and epithelioid histiocytes arranged in a palisaded pattern, with central necrosis (Figure 1) similar to the features of a rheumatoid nodule.
Rheumatoid nodule and subcutaneous granuloma annulare: a comparative histologic study.