Areas with rhabdoid
pattern where constituted of discohesive cells arranged in loose sheets.
Wiim's Tumour with Rhabdoid
Elements (H & E, 40X)
(2012) A remarkably simple genome underlies highly malignant pediatric rhabdoid
Their little boy Oliver was diagnosed with a malignant rhabdoid
Different types of pediatric renal tumors are known, the commonest of which is Wilms tumor or nephroblastoma, other less common tumors are nephroblastomatosis, rhabdoid
malignant tumor, clear cell sarcoma, congenital mesoblastic nephroma and multilocular cystic nephroma3.
(9) Individual tumor cells are often round to oval with scant or moderate eosinophillic cytoplasm and pleomorphic nuclei with rhabdoid
and epitheloid cells scattered at periphery.9 ESMC expresses neuroendocrine differentiation with strong immunopositivity for vimentin and synaptophysin (7) and weak or focal positivity for EMA and S-100.7 Myxoid matrix with lobulated neoplastic cells is also seen in chordoma, parachordoma, chordoid meningiomas, and myxopapillary ependymoma.
Lewin, "Malignant mixed epithelial and stromal tumor of the kidney with rhabdoid
features: report of a case including immunohistochemical, molecular genetic studies and comparison to morphologically similar renal tumors," Human Pathology, vol.
Kimura et al., "Epithelioid/ rhabdoid
glioblastoma: a highly aggressive subtype of glioblastoma," Brain Tumor Pathology, vol.
The others were diagnosed as angiosarcoma, undifferentiated pleomorphic sarcoma, solitary fibrous tumor, low-grade fibromyxoid sarcoma, malignant peripheral nerve sheath tumor, breast phyllodes tumor, round cell sarcoma with CIC rearrangement, neuroblastoma, malignant extrarenal rhabdoid
tumor, and myxofibrosarcoma.
cells with typical eccentric nuclei and cytoplasmic inclusions were seen scattered throughout.
The specimen was then sent for an outside consultation, and the diagnosis was edited to epithelioid sarcoma with rhabdoid
features (proximal type).