reward deficiency syndrome

reward deficiency syndrome

A name for a relative failure of the dopaminergic system which plays a major part in brain-reward mechanisms. The syndrome, which has been linked to dysfunction of the D2 dopamine receptors, includes various conditions, such as drug and alcohol abuse, smoking, obesity, pathological gambling and attention deficit hyperactivity disorder, in which the subject seems to be unusually concerned to achieve reward. The D2 dopamine receptor gene is on chromosome 11 and has multiple allelic forms. Variants have been correlated with these and other reward-seeking behaviours.
References in periodicals archive ?
ADHD can be seen as a reward deficiency syndrome, which is the breakdown of the reward "cascade"-the patient is not getting rewarded by typically rewarding activities, which leads to impulsivity, other clinical correlates, and addictive behaviors.
A newer supplement for brain healing is the natural product Synaptamine, developed by Ken Blum, who has been a noted researcher and coined the phrase reward deficiency syndrome to describe the impulsive and compulsive disorders and personality disorders associated with a decrease in dopamine (DRD2) receptors in the brain.
Synaptamine contains amino acids, cofactors, and vitamins that help improve reward deficiency syndrome.
This product is developed by a team of qualified doctors who have studied addiction, genetics, neurological science, Reward Deficiency Syndrome (RDS), and dopamine effects on the brain.
The D2 dopamine receptor gene as a determinant of reward deficiency syndrome.
Other topics include cancer biomarkers, cardiac channelopathies, and the neurogenetics of reward deficiency syndrome.
Researchers have proposed that defects in this system can result in a reward deficiency syndrome and that adults with this syndrome are at higher risk for abuse of psychoactive substances.
Neurogenetics and nutrigenomics of reward deficiency syndrome.
This neuroadaptation can be long lasting, resulting in reward deficiency syndrome, a constant state of withdrawal or deprivation during which the person is nonresponsive to everyday activities that would normally bring a moderate level of pleasure.
Since that time, there have been many articles on the role of Reward Deficiency Syndrome (RDS), as described earlier (Blum et al.
This phenomenon has been referred to as reward deficiency syndrome (Blum et al.