revertant


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re·ver·tant

(rē-ver'tănt),
In microbial genetics, a mutant that has reverted to its former genotype (true reversion) or to the original phenotype by means of a suppressor mutation.
[L. revertans, pres.p. of reverto, to turn back]
Farlex Partner Medical Dictionary © Farlex 2012

revertant

(rĭ-vûr′tnt)
adj.
Having reverted to the normal phenotype, usually by a second mutation: a revertant mutant; revertant cells.
n.
A revertant organism, cell, or strain.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

re·ver·tant

(rē-vĕr'tănt)
microbial genetics A mutant that has reverted to its former genotype (true reversion) or to the original phenotype by means of a suppressor mutation.
[L. reverto, to turn back]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

revertant

see REVERSION.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Patient discussion about revertant

Q. Could it revert back to my mom? If yes, how to deal with it? my mom’s lump is removed, chemotherapy is just over and she is getting well. My mom is a tea and coffee lover. But with doctors advice she did cut down on tea/coffee say once in a week. Could it revert back to my mom? If yes, how to deal with it?

A. Tea and coffee do not have any impact on the breast cancer recurrence. Caffeine in the coffee needs to be monitored as it increases some symptoms for breast lumps which are not cancerous but can increase the risk for cancer. It doesn’t show any link in cancer recurrence. Tea has nothing to do with cancer recurrence rather it is being proved having green tea helps in reduction of the tumor. Your mom can have green tea, if she feels unsafe to have coffee or normal tea.

More discussions about revertant
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References in periodicals archive ?
A concentration-related increase in the number of revertant colonies per plate in at least one strain with or without metabolic activation system;
(11) That includes the observation of trace amounts of dystrophin expression in myofibers of patients with DMD, (23) as well as the prevalence of revertant fibers.
No precipitation was observed at test item concentrations up to 5 mg/plate in the precipitation test, and no dose-related decreases in revertant colony numbers compared to the negative control or effects on background lawn development, with or without S9-mix, were observed at any test item concentration in tester strain TA100 in the preliminary cytotoxicity test (data not shown).
However, a drawback preventing a useful application of such strategies is represented by the revertant nature of metabolically adapted LSC, which implies the risk of seriously damaging the HSC pool while trying to eradicate LSC.
Table 2: Mutagenic potential expressed by mean and standard deviation of revertant colonies per plate and mutagenicity index in the absence of metabolic activation of the ethanolic extract of Cochlospermum regium leaves.
Also, a major reduction of the induced revertants was obtained for TA97, TA98, and strains even in the absence of metabolic activation (Table 2).
Evaluation of nonsynonymous SNVs confirmed some outbreak viruses to be revertants of the vaccine AHSV-1 strain toward the virulent parental type.
A more practical approach, i.e., a transient expression assay skipping the revertant selection by P12/UV, (39) was also developed for further isolation of PEX cDNAs including nine others, PEX1, PEX3, PEX5, PEX6, PEX12, PEX13, PEX14, PEX19, and PEX26 (21), (34), (40)-(48) (Table 3; Fig.
Consumption of meat mutagens was estimated by multiplying the frequency of cooked meat intake from the cooking questionnaires with measured individual heterocyclic amine (ng/g meat) or MDM levels (revertant colonies/g meat) and standard (medium) portion size from the CHARRED Database (NCI 2006).
The results showed that only positive control plates induced an increase in the number of revertant colonies relative to the negative control, indicating mutagenic activity reaching a mutagenic ratio of higher than 2.0 (Table 7).
This confirmed Darwin's great predictive insight in the simplest forms of life, and it gave me the idea to see whether in the same way, Revertant normal cells might arise from the descendants of a tumor cell, in advance and at random.
Klein-Szanto, "Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: not an invariant correlation with metastasis," International Journal of Cancer, vol.