revertant


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re·ver·tant

(rē-ver'tănt),
In microbial genetics, a mutant that has reverted to its former genotype (true reversion) or to the original phenotype by means of a suppressor mutation.
[L. revertans, pres.p. of reverto, to turn back]

revertant

(rĭ-vûr′tnt)
adj.
Having reverted to the normal phenotype, usually by a second mutation: a revertant mutant; revertant cells.
n.
A revertant organism, cell, or strain.

re·ver·tant

(rē-vĕr'tănt)
microbial genetics A mutant that has reverted to its former genotype (true reversion) or to the original phenotype by means of a suppressor mutation.
[L. reverto, to turn back]

revertant

see REVERSION.

Patient discussion about revertant

Q. Could it revert back to my mom? If yes, how to deal with it? my mom’s lump is removed, chemotherapy is just over and she is getting well. My mom is a tea and coffee lover. But with doctors advice she did cut down on tea/coffee say once in a week. Could it revert back to my mom? If yes, how to deal with it?

A. Tea and coffee do not have any impact on the breast cancer recurrence. Caffeine in the coffee needs to be monitored as it increases some symptoms for breast lumps which are not cancerous but can increase the risk for cancer. It doesn’t show any link in cancer recurrence. Tea has nothing to do with cancer recurrence rather it is being proved having green tea helps in reduction of the tumor. Your mom can have green tea, if she feels unsafe to have coffee or normal tea.

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References in periodicals archive ?
Evaluation of nonsynonymous SNVs confirmed some outbreak viruses to be revertants of the vaccine AHSV-1 strain toward the virulent parental type.
The reason is simple: With big-data analysis of whole genomes, a comparison of normal, tumor, and revertant lines has at last opened the possibility of finding mechanisms of reversion, and from there, the possibility of designing drugs to revert tumor cells rather than killing them.
The colonies were counted and the results were expressed as the number of revertant colonies per plate.
There were no revertants exceeding three times the background average either with or without the metabolic activation system.
In the experimental design used, the independent variable was the concentration of the samples of the Cauca River and the response variable was the number of spontaneous revertants of strains in each treatment, with and without enzymatic activation.
In the first AAV-mediated gene therapy trial for this disease, a surprising finding was that hidden epitopes of expressed dystrophin, usually found on revertant fibres, proved to be immunogenic for some individuals.
Smith FJ, Morley SM, McLean WH: Novel mechanism of revertant mosaicism in Dowling-Meara epidermolysis buuosa simplex.
After incubation, the number of revertant bacteria colonies, which signifies mutation events, was counted.
1) An outbreak of poliomyelitis that was due to a revertant virus (ie, mutated so no longer as attenuated) from oral poliovirus vaccine strain 1 occurred fairly recently in the Dominican Republic and Haiti.
It is likely that reverted oysters would exhibit lower fecundity than diploid oysters because revertant oysters are mosaic; i.
Given the problems of long-term carriers, revertant strains, and limitations of surveillance, it is very difficult to certify an area as polio free, even without the possibility that someone may be developing a biological weapon using polio.
We determined if the chimeric flower phenotype would be expressed or become inactivated when crossed to stable pink (wp*) or purple (Wp*) flowered revertant lines derived from LN89-5320-8-53.