retroperitoneal sarcoma

retroperitoneal sarcoma

A nonspecific term for any sarcoma arising in the retroperitoneal region, which comprises 15% of all sarcomas (of 8,600 cases/year, USA).
 
Clinical findings
Often asymptomatic abdominal mass; average age, 50.

Prognosis
65% to 80% of cases achieve complete resection; 5-year local recurrence, ±50%; 5-year survival, ±50%.

Histological types of retroperitoneal sarcoma
• Liposarcoma—41%;
• Leiomyosarcoma—28%;
• Malignant fibrous histiocytoma (MFH)—7%;
• Fibrosarcoma—6% (MFH and fibrosarcoma are now viewed as synonyms);
• Malignant peripheral nerve sheath tumour—3%.
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References in periodicals archive ?
The role of neoadjuvant therapy is important in cases of retroperitoneal sarcoma, (8) but rarely RCC.
12) The follow-up for retroperitoneal sarcoma normally includes CT investigations every 3 to 6 months for 2 to 3 years.
Other topics include the management of the axilla and retroperitoneal sarcoma, the role of radiotherapy in breast cancer, and a review of recent randomized trials.
An en bloc resection of the left colon, retroperitoneal sarcoma, left kidney and adrenal gland with end colostomy were completed.
Intestinal perforation represents a rare presenting complication of retroperitoneal sarcoma.
Local recurrence is not a death sentence in extremity sarcoma as it often is in retroperitoneal sarcoma.
The differential diagnoses include Wilm's tumour, neuroblastoma, renal cell carcinoma (RCC), malignant lymphoma, metastatic renal involvement from sarcoma elsewhere in the body, and renal involvement by a primary retroperitoneal sarcoma.
8) This creates a pathway for extension of retroperitoneal sarcomas into the paratesticular region.
In addition, the Mobetron will also be used for advanced and recurrent cancers, such as recurrent head and neck cancer, pancreatic cancer, recurrent rectal cancer, extremity and retroperitoneal sarcomas, and pediatric cancers.
The Mobetron at UCSF has been treated hundreds of advanced and recurrent cancers, such as recurrent head and neck cancer, mesothelioma, recurrent rectal cancer, neuroblastoma, extremity and retroperitoneal sarcomas, and pediatric cancers.
In this location, 90% of malignancies are retroperitoneal sarcomas and about 10% are extragonadal germ cell tumours.

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