The department was thrilled that the baby would live, but heartbroken when she developed signs of a newly discovered disease (called Retrolental
Fibroplasia at the time, now called Retinopathy of Prematurity or ROP) that usually caused blindness.
They experience a number of long-term health problems at a higher rate than singletons, including cerebral palsy and oxygen-induced retrolental
fibroplasia, a form of blindness.
Flower R, Blake D (1981) Retrolental
fibroplasia: evidence for a role of the prostagladin cascade in the pathogenesis of oxygen-induced retinopathy in the newborn beagle.
The two babies who survived after PPROM at 20-21 weeks remained in the hospital for 117 and 182 days, respectively Both had chronic lung disease, respiratory distress syndrome, intraventricular hemorrhage, and retrolental
Still, all antihistamines should be avoided if premature labor occurs because of a possible association between retrolental
fibroplasia in premature babies exposed to antihistamines within 2 weeks of birth.
A significantly increased risk of retrolental
fibroplasia in premature babies whose mothers had taken a first-generation antihistamine during the last 2 weeks of gestation was also found in a 1986 multicenter study of premature newborns.
The authors do mention that 11 of the 14 congenitally blind participants had retrolental
fibroplasia (also known as retinopathy of prematurity), a condition caused by an excessive concentration of oxygen in the incubator into which the person had been placed as a prematurely born neonate.
In addition, it promotes healthy skin and hair, and helps to prevent anemia and retrolental
fibroplasia, an eye disorder that can affect premature infants.
fibroplasia: What we know and what we don't know.
Researchers termed the condition retrolental
Fibroplasia (retinopathy of prematurity) - Occurs