retrograde degeneration

ret·ro·grade de·gen·er·a·tion

retrograde cell degeneration with chromatolysis of Nissl bodies and peripheral displacement of the nucleus of the cell of origin of a nerve fiber injured or sectioned.
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As a model of retrograde degeneration, the L4-L5 ventral rhizotomy is similar to axotomy paradigms in the CNS, in which loss of differentiated transmitter phenotype (usually an early change) is accompanied by alterations in the neuronal cytoskeleton and, eventually, cell death (Gage et al., 1986; Koliatsos et al., 1989).
Impairment Induction by Axotomy in Motor Functional and Histological Anterior Horn of Spinal Cord Structure/Induccion del Deterioro por Axotomia en la Estructura Motora Funcional e Histologica del Asta Anterior de la Medula Espinal
Because RD increases are primarily caused by demyelination [40, 41], our findings are strongly suggestive of demyelination caused by secondary Wallerian degeneration or retrograde degeneration after SCI.
Hepp Reymond, "Retrograde degeneration of the pyramidal tract cells in the motor cortex of apes (Macaca fascicularis)," Acta Anatomica, vol.
Brain White Matter Impairment in Patients with Spinal Cord Injury
An important prerequisite for axonal regeneration would be the prevention of retrograde degeneration that could cause neuronal death or atrophy impeding the activation of axonal regrowth.
Retrograde Activation of the Extrinsic Apoptotic Pathway in Spinal-Projecting Neurons after a Complete Spinal Cord Injury in Lampreys
It is inferred that retrograde degeneration of nerve cell is a new form of cell death in "tau disease" such as AD (Kaminska et al.
Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain
In untreated brain injury, not only do brain cells die in the injured area, but nerve cells in other brain regions connected by nerve fibers to the injured area also die by a process known as retrograde degeneration. Dr.
Progesterone: may improve outcomes from brain injury
Nerve conduction is interrupted and the nerve fiber undergoes retrograde degeneration (Wallerian degeneration).
Recurrent laryngeal nerve paralysis: Current concepts and treatment: Part I--Phylogenesis and physiology

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