Computed tomographic scanning was used to reveal craniofacial or temporal bone malformations, while magnetic resonance imaging helped to rule out retrocochlear
pathology such as vestibular schwannoma, stroke, and/or demyelinating disease.
Otoacoustic emission provides reliable evidence for the identification and diagnosis of cochlear and retrocochlear
The subjects were excluded when they met the following criteria based on medical records: 1) History of ototoxic drug use or otologic disease, 2) Familial history of hearing loss, 3) Prior steroid use before treatment with ITD, 4) The presence of chronic otitis media, Meniere's disease, or retrocochlear
lesion, and 5) Possible somatic tinnitus or objective tinnitus.
Cochlear and retrocochlear
SNHL were differentiated, and those with retrocochlear
hearing loss were excluded from the study.
The ABR has a wide range of clinical applications, including intraoperative monitoring, (10) screening for retrocochlear
pathology, (11) and universal newborn hearing screening.
6] OAEs are altered if there is damage to the cochlea, but they are not disturbed if the retrocochlear
neural pathway is affected.
Central auditory pathway pathologies (aka retrocochlear
7) However, if a retrocochlear
hearing deficit is detected, auditory brainstem response testing is useful to help locate the lesion.
Criteria for excluding potential subjects from this study were (1) cognitive, physical, or psychological inability to participate; (2) inability to provide reliable behavioral threshold responses (patient did not meet intrasession reliability of [+ or -]5 dB using the manual testing mode); and (3) subject or medical record report of Meniere's disease, retrocochlear
disorder, or active or recent history of middle ear disorder.
The overall results of such studies have demonstrated cochlear (64% of cases), vestibular (28%), retrocochlear
(4%), and external and middle ear (4%) disease involvement.
Hearing loss is categorised as conductive (CHL) or sensorineural (SNHL), with SNHL being further subdivided as cochlear or retrocochlear
In this study, SDS in the audiometric test did not show retrocochlear
involvement, but auditory brainstem response (ABR) assessment would have helped to distinguish not only the central pathways but also the brainstem neural integrity.