an oxidoreductase catalyzing interconversion of retinal and NADH to retinol and NAD+.
ADH7A gene on chromosome 4q23-q24 that encodes class-IV alcohol dehydrogenase 7 mu or sigma subunit, which like other alcohol dehydrogenases metabolises various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. ADH7 is inefficient in ethanol oxidation; it is the most active as a retinol dehydrogenase and may participate in synthesising retinoic acid—which is required for cellular differentiation. ADH7 is highly expressed in the stomach.
ret·i·nol de·hy·dro·gen·ase(ret'i-nol dē'hī-droj'ĕn-ās)
An oxidoreductase-catalyzing interconversion of retinal and NADH to retinol and NAD+.