retinol binding protein


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retinol binding protein (RBP)

A single-chain polypeptide glycoprotein secreted in fat cells and the liver. It is a member of the alpha globulin family of plasma proteins. It binds and solubilizes retinol and protects it from oxidation. RBP 4 is elevated before the development of frank diabetes and appears to indicate insulin resistance.
References in periodicals archive ?
The RBP7 is a member of the retinol binding protein family The retinoids play roles in vision, growth, reproduction, and cellular differentiation beginning in early development [16].
Mahmoudi, "Retinol binding protein 4 in relation to diet, inflammation, immunity, and cardiovascular diseases," Advances in Nutrition, vol.
Investigation of the relationship between retinol binding protein 4, metabolic syndrome and insulin resistance in Iranian obese 5-17 year old children.
Caption: Figure 4: Validation of Kininogen-1, Keratin 1, Myeloperoxidase, Retinol binding protein 4, Serum amyloid A protein, and bradykinin in serum.
Im, "Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents," Metabolism, vol.
A1M: Alpha- ([alpha]-) 1 microglobulin B2-M: Beta ([beta]) 2-microglobulin DN: Diabetic nephropathy eGFR: Estimated glomerular filtration rate KIM-1: Kidney injury molecule-1 L-FABP: Liver-type fatty acid binding protein NAG: N-Acetyl-beta-glucosaminidase NGAL: Neutrophil gelatinase associated lipocalin RBP: Retinol binding protein UACR: Urinary albumin-creatinine ratio.
Quantification of patients' plasma proteins: To evaluate the protein metabolism before and after rhGH therapy plasma levels of retinol binding protein (RbP) transferrin (TRF) serum albumin (PRE) and albumin (ALB) were tested.
Zinc deficiency reduces hepatic cellular retinol binding protein in rats.
Retinol binding protein 4 (RBP4), another member of the lipocalin family, has recently been added to the list of adipokines that may link obesity with insulin resistance and type 2 diabetes [1,2].
Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. J Nutr.
Retinol binding protein as a surrogate measure for serum retinol: studies in vitamin A-deficient children from the Republic of the Marshall Islands.
This has been documented by Blumsohn, et al (2), who noted that total protein concentrations, albumin, retinol binding protein, and [[beta].sub.2] microglobulin measurements were all significantly higher in post-coital initial urine samples compared to midstream samples collected from the same individuals without prior intercourse/ejaculation.