retinoids


Also found in: Dictionary, Encyclopedia.
Related to retinoids: tretinoin

ret·i·noids

(ret'i-noydz),
A class of keratolytic drugs derived from retinoic acid and used for treatment of severe acne and psoriasis.

ret·i·noids

(ret'i-noydz)
A class of keratolytic drugs derived from retinoic acid used for treatment of severe acne and psoriasis.

retinoids

A class of compounds containing 20 carbon atoms and related to RETINAL and vitamin A. They include retinol, TRETINOIN, isotretinoin, etretinate, acitretin and arotinoid. Retinoids bind to cell nuclear retinoid receptors and the latter bind to DNA. The effect of the retinoids is to promote transcription of DNA in much the same way as do steroids and thyroid hormone. They have a wide range of biological actions and have been found useful in ACNE, certain skin cancers, PSORIASIS, skin ageing and other skin disorders. Retinoids taken in the first three weeks of pregnancy are liable to cause abortion or serious fetal defects. For this reason the use of systemic retinoids in women is strictly controlled.

Retinoids

A derivative of synthetic Vitamin A.
Mentioned in: Ichthyosis

retinoids

vitamin A analogues; used to treat recalcitrant acne vulgaris; should not be used during pregnancy as they are teratogenic

retinoids (reˑ·t·noidz),

n.pl compounds in the vitamin A family.

ret·i·noids

(ret'i-noydz)
Keratolytic drugs used to treat severe acne and psoriasis.
References in periodicals archive ?
Most of the research on how antioxidants and retinoids work takes place in the laboratory and uses hamsters, human tissue samples, and cell cultures.
Several clinical research studies have shown that retinoids trigger changes in the skin to make it look clearer and youthful.
Treatment should include oral antibiotics with topical retinoids plus BP, with or without topical antibiotics.
Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids.
But acne vulgaris is reported in more than three-quarters of children in this age range, so it's not unreasonable to think about treating them with a topical retinoid.
It is certainly the case that non-specific irritants such as sodium lauryl sulphate [8] and mechanical stimulation with aluminium oxide particles in soap paste [9] can emulate the epidermal hyperproliferative and hyperplasiogenic effects of topical retinoids.
Acne on the back or chest often does not respond well to retinoids or benzoyl peroxide, and teenage boys often won't adhere to any topical therapy (including topical antibiotics), so systemic antibiotics may be needed before you can get them to transition to topical therapies, Dr.
Tazarotene is the least tolerable of the retinoids.
Drugs such as botulinum toxins, retinoids, acid peels, 5-alpha reductase and lipase inhibitors associated with cutaneous ageing, photodamage, pigmentation defects, alopecia, and the lipodermal disorders of obesity and gynoid lipodystrophy are critically discussed to provide a detailed analysis of the high-growth market sector estimated at US$1.
Ingredients that should be used prior to wounding include retinoids such as tretinoin and retinol.
A combination of retinoids and alpha hydroxy acids provide skin texture improvement benefits too.
Human epidermis contains endogenous retinoids (retinol and retinyl esters) and carotenoids (mostly beta-carotene).

Full browser ?