retinoic acid


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to retinoic acid: vitamin A

retinoic acid

 [ret″ĭ-no´ik]
an oxidized derivative of retinol, believed to be the form of vitamin A that plays a role in the development and growth of bone and in the maintenance of normal epithelial structures. The all-trans isomer is called tretinoin and used as a keratolytic and antineoplastic agent. The 13-cis isomer is called isotretinoin and used as a treatment for acne.

ret·i·no·ic ac·id

(ret'i-nō'ik as'id),
Vitamin A1 acid; used topically to treat acne.
Synonym(s): vitamin A1 acid

retinoic acid

/ret·i·no·ic ac·id/ (ret″ĭ-no´ik) an oxidized derivative of retinol, believed to be the form of vitamin A that plays a role in the development and growth of bone and in the maintenance of normal epithelial structures. In pharmacology, it often denotes the all-trans isomer (tretinoin); the 13-cis isomer is usually called isotretinoin.

retinoic acid

(rĕt′n-ō′ĭk)
n.
1. A vitamin A derivative, C20H28O2, that serves as a regulator of morphogenesis and functions in the growth and development of bone and the maintenance of epithelium.
2. Either of two isomers of this compound, tretinoin or isotretinoin, that are used as drugs chiefly to treat acne. In both senses also called vitamin A acid.

(all-trans-)retinoic acid

Tretinoin The natural form of vitamin A, which transports monosaccharides in glycoprotein synthesis, as occurs in the turnover of mucosal epithelia of the oral cavity, respiratory and urinary tracts. See Retinal, Retinoic acid embryopathy, Tretinoin, Vitamin A.

ret·i·no·ic ac·id

(ret'i-nō'ik as'id)
Retinaldehyde in which the terminal -CHO has been oxidized to a -COOH; used topically in the treatment of acne; plays an important role in growth and differentiation.
Synonym(s): vitamin A1 acid.

Retinoic acid

Vitamin A1 acid which is used topically to treat acne.
Mentioned in: Warts

ret·i·no·ic ac·id

(ret'i-nō'ik as'id)
Agent used topically to treat acne.
Synonym(s): vitamin A1 acid.

retinoic acid

form of vitamin A, derived from retinal. See tretinoin.

Patient discussion about retinoic acid

Q. has anyone here tried crossfit? its a way of cross training that is supposed to work your wholebody. I am interested in trying it but want some feedback from my friends here first.

A. cool, I am planning on a class this Friday.

More discussions about retinoic acid
References in periodicals archive ?
The company is advancing a novel retinoic acid receptor gamma agonist to address diseases of heterotopic ossification, including fibrodysplasia ossificans progressiva.
Without production of the hormone retinoic acid, females are burning fat and expending the energy in the form of heat.
4) The result is a fusion transcript between the retinoic acid receptor, or RARA (RAR[alpha]) and the promyelocytic gene.
Our studies show that HSV-2-infected dendritic cells secrete retinoic acid and thereby increase the presence of integrin [alpha]4[beta]7 on T cells.
The data provides a mechanistic explanation to the nearly 100 year old question of why vitamin A deficiency causes so many pathologies that are independent of retinoic acid action.
APL, which represents 10-15% of all AML, is characterized by chromosomal translocations fusing retinoic acid receptor-alpha (RAR[alpha]) gene on chromosome 17 and one of four different genes, including promyelocytic leukemia (PML), promyelocytic zinc finger (PLZF), nucleophosmin (NPM), nuclear matrix associated (NuMA), or signal transducer and activator of transcription 5b (Stat5b) gene [1-5].
Retinoic acid plays an important role in mammalian development and cellular growth and differentiation.
Laboratory tests showed that treatment with vitamin A, in the form of retinoic acid, turned the normally scaly lining of the oesophagus into a glandular lining, like that found in the stomach or intestine.
Rambazole is a novel retinoic acid metabolism-blocking agent (RAMBA).
Effects of vitamin A on aged skin are well documented; however, retinoic acid, a form of vitamin A, has serious side effects and is not allowed in skincare preparations.
Many treatments have been undertaken, including surgery, laser ablation, steroid injection, radiation, interferon, cryotherapy, pressure therapy, and retinoic acid among many others, but recurrences remain common.

Full browser ?