Caption: Figure 3: Low-power histologic aspect of the lesion (a) demonstrating exophytic growth in a verrucous/warty pattern with epithelial projections, hyperparakeratosis, orange keratin plugs, and elongated, thickened epithelial rete ridges
(hematoxylin and eosin stain x150).
Caption: Figure 4: Photomicrograph showing parakeratinised stratified squamous epithelium with bulbous rete ridges
lining the cystic lumen.
Left upper anterior gingival mucosal mass, 6 mm, from a 2week-old white girl, demonstrating attenuated overlying squamous epithelium with absent rete ridges
(hematoxylin-eosin, original magnification X2).
The histopathologic picture showed acanthosis, elongation and anastomosing rete ridges
and microabscessses in the superficial layers of the epithelium.
of Cases 1 Atrophy 14 2 Hyperkeratosis 47 3 Parakeratosis 11 4 Hypergranulosis 43 5 Acanthosis 40 6 Spongiosis 6 7 Papillomatosis 2 8 Elongated rete ridges
(saw tooth) 4 9 Loss of rete ridges
2 10 Civatte bodies 17 11 Vacuolar basal cell degeneration 49 12 Max joseph space 2 13 Basement membrane thickening 2 14 Follicular plugging 5 Table 5: Dermal histopathological changes Sl.
Histopathology showed hyperkeratosis, parakeratosis, elongation of rete ridges
and mild perivascular mononuclear infiltrate.
Pathological examination of the left helix showed that the epidermis was thin, with flattening of the rete ridges
and many epithelioid granulomas with local caseous necrosis, accompanied by infiltration of lymphocytes into the dermis, multinucleated giant cells were not remarkable [Figure 1]b.
Histopathology is diagnostic testing using a distinctive form of acanthosis, characterized by an irregular elongation of thin branching rete ridges
, with a concentration of melanin at the tips.
Histopathological examination of a punch skin biopsy showed hyperkeratotic epidermis with focal parakeratosis, irregular acanthosis, and elongated rete ridges
. In the dermis, periadnexal and perivascular lymphocytic infiltration was seen.
Histopathologic examination of a skin biopsy from the comedonal and pigmented lesions on back of the neck of the proband in family 1 revealed a dilated hair follicle with follicular plugging and acanthosis with downward elongations of rete ridges
in a reticulated or fenestrated pattern and a few horn cysts [Figure 2]h.
Histopathological examination showed the presence of a central column of hyperkeratosis and parakeratosis, the cornoid lamella and reduced thickness of granular layer along with elongated rete ridges
. Dermis showed scanty inflammatory cell infiltrate.
The histopathological examination showed normal stratum corneum, focal areas of atrophy in stratum spinosum, effaced rete ridges
, hyperpigmented basal layer, eosinophilic amorphous collagen fibres in dermis, perivascular and periappendageal lymphohistiocytic infiltrate.