resveratrol


Also found in: Dictionary, Wikipedia.

resveratrol

(rĕz-vîr′ĭ-trôl′, -trŏl′, -trōl′)
n.
A polyphenolic compound, C14H12O3, that is found in grapes, mulberries, peanuts, and other plants or food products, especially red wine, has antioxidant and anti-inflammatory properties, and may protect against cancer and cardiovascular disease.
A naturally occurring phytoalexin and antioxidant produced by some higher plants—e.g., grapes (Vitis vinifera)—in response to injury or fungal infection

resveratrol

Nutrition A phytochemical in grapes which may be partly responsible for the health benefit attributed to red wine. See Red wine.

resveratrol

A molecule present in plants that has been shown to activate SIRTUINS in animals in a manner similar to the effect of calories restriction. Resveratrol enhances vitality and extends life span in worms, fruit flies and some fish. It also diminishes the malign effects of a high-calorie, high-fat diet in mice, protects against insulin resistance and diabetes, and improves cognition.
References in periodicals archive ?
Further, as a small molecule with high target tissue and blood-brain barrier penetration, resveratrol can find utility as monotherapy or as an adjunct to biological treatment or other approaches that may not address all patient needs.
And here's something even more amazing: If you ever do have a heart attack, resveratrol actually protects your heart from damage.
Based on very successful pre-clinical data, the company expects the resveratrol administration in the JOTROL formulation will deliver the necessary levels of resveratrol in plasma without generating any severe GI side-effects.
With strong research showing resveratrol can boost skin elasticity, reduce age spots and wrinkle depth, and improve skin smoothness, Reserol is proving a popular product in the healthy ageing category.
org/news/can-the-antioxidant-resveratrol-reduce-artery-stiffness-in-diabetics) study , presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology and Peripheral Vascular Disease 2017 Scientific Sessions in Minnesota, researchers found a 300 milligram (mg) per day dose of resveratrol decreased aortic stiffness by 9 percent in type 2 diabetes patients.
Resveratrol, which is found in red wine, grapes, and peanuts, among other foods, makes obese mice live longer.
Several studies have demonstrated that resveratrol possesses potent antioxidant, anticarcinogenic, and anti-inflammatory, as well as antimicrobial characteristics.
Resveratrol has been characterized as a pleiotropic agent that exhibits multiple targets in cancer cells with marginal effects on non-mitotic cells [10-12].
The enzyme triumvirate, PGCla-SIRTl-AMPK plays a crucial role in mitochondrial biogenesis and resveratrol aids greatly in the process by enhancing the expression of these three enzymes.
Study design: The effect resveratrol on STAT3 activation, associated protein kinases, phosphatases, cellular proliferation and apoptosis was investigated.
In studies involving diabetic mice, resveratrol has been shown to improve insulin sensitivity by inhibiting the protein tyrosine phosphatase 1B (PTP1B) gene.