endonuclease(redirected from restriction e)
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Related to restriction e: Restriction mapping
an enzyme that cleaves internal bonds of polynucleotides.
restriction e's enzymes that cleave large DNA molecules at specific sequences of four to six nucleotides. See also recombinant dna technology.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An enzyme (phosphodiesterase) that cleaves the internal phosphodiester bonds in a DNA molecule, thus producing DNA fragments of varying size. Compare: exonuclease.
Farlex Partner Medical Dictionary © Farlex 2012
endonuclease(ĕn′dō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
Any of a group of enzymes that catalyze the hydrolysis of bonds between nucleotides in the interior of a DNA or RNA molecule.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
A nuclease (phosphodiesterase) that cleaves polynucleotides (nucleic acids) at interior bonds, thus producing polynucleotide or oligonucleotide fragments of varying size.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
endonucleasea NUCLEASE that cleaves PHOSPHODIESTER BONDS from within nucleic acid molecules. See also RESTRICTION ENDONUCLEASE, compare EXONUCLEASE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
A nuclease (phosphodiesterase) that cleaves polynucleotides (nucleic acids) at interior bonds.
Medical Dictionary for the Dental Professions © Farlex 2012