The respiration trace was recorded and used to inform respiratory triggering.
Respiratory triggering, whereby the EPI readout was acquired during the plateau phase of respiration, was found to reduce signal fluctuation at the base of the brain (Supplementary Figure 1).
The use of respiratory triggering also relies on a reasonably stable respiratory cycle, which was reliably achieved at -60 breaths per minute with 1.2-1.5% isoflurane concentrations for up to two hours.
Finally, from a technological perspective, currently, IVIM image acquisition methods include free-breathing, breath-hold, and respiratory triggering
. Respiratory triggering
is used widely in clinical work and can produce high image quality and perfect signal-noise ratio compared with free-breathing and breath-hold; however, a disadvantage of respiratory triggering
is that its parametric reproducibility is inferior to the latter two methods.
Because of the long scan time required for 3D implementation, respiratory triggering
is used to remove respiratory motion artifacts.
The effect of simultaneous use of respiratory triggering
in diffusion-weighted imaging of the liver.
The 3D FRFSE- XL is a 3D FSE (Fast Spin Echo) pulse sequence which operate swith the respiratory triggering
, ASSET (Arraycoil Spatial Sensitivity Encoding Technique) and facilitates fast recovery.