Among globally disseminated pathogens, HGT facilitates combination of the most effective antibiotic resistance genes from diverse geographies into multidrug resistance plasmids
that spread between strains.
This shows that not only do these organisms carry resistance plasmids
, they have the ability to transfer these plasmids and thus their resistance to other organisms whether pathogenic or not.
CTX-M-9] are linked to class 1 integrons containing CR1 associated with defective transposon derivatives from Tn402 located in early antibiotic resistance plasmids
of IncHI2, IncP1-a, and IncFI Groups.
Resistance genes are either carried on the chromosomes of wild-type bacteria or on elements of extachromosomal, sometimes extraneous origins, such a resistance plasmids
and transposons (8).
Transfer of multiple drug resistance plasmids
between bacteria of diverse origin in natural microenvironments.
The presence of resistance plasmids
(R-plasmids) is a significant feature of this organism (15,16).
Other workers reported that transmission of resistance plasmids
of Escherichia coli from poultry to human intestines commonly occurs (Tabatabaei and Nasirian, 2003).
There is an urgent need for expanded resistance surveillance for carbapenemase-producing organisms and their resistance plasmids
in food products that are not captured under current programs.
Replicon typing through a published multiplex PCR system revealed a replicon I1 from the Tn6092harboring resistance plasmids
in SC-B134 and SC-B136 (Table 1; Figure 2, panel C) (10).
Although Klebsiella with plasmid-mediated carbapenem resistance is a major risk to hospitalized patients, spread of these resistance plasmids
into Escherichia coli poses an even greater public health threat because resistant E.
CTX-M-9] are linked to class integrons containing CRI associated with defective transposon derivatives from Tn402 located in early antibiotic resistance plasmids
of IncHI2, IncP1-alpha, and IncFI groups.
Distribution of oxytetracycline resistance plasmids
between aeromonads in hospital and aquaculture environments: implication of Tn1721 in dissemination of the tetracycline resistance determinant tetA.