resiniferatoxin


Also found in: Acronyms, Wikipedia.

resiniferatoxin

Neurology An agent for treating urge incontinence in Pts with neurologic disease–eg, spinal cord injury and multiple sclerosis
References in periodicals archive ?
Resiniferatoxin could be administered to patients at doses and for intervals that result in maximum protection and fewest side effects.
Chen, "Resiniferatoxin induces paradoxical changes in thermal and mechanical sensitivities in rats: mechanism of action," The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.
Keller et al., "Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist," PAIN, vol.
Euphorbium: modern research on its active principle, resiniferatoxin, revives an ancient medicine.
Agents to destimulate the nerve endings, such as lidocaine, resiniferatoxin, and botulinum toxin, have been administered intravesically with some success.
Intravesical therapies with verapamil, lidocaine, and oxybutynin as well as newer agents of resiniferatoxin and capsaicin are effective but more inconvenient.
Sorrento Therapeutics announced that review of early results from an on-going "declawed cat pain trial" prompted management to assign a high priority to exploring the use of resiniferatoxin as a local nerve block injection for the control of neuropathic post-amputation residual limb pain in humans.
Petho, "Effect of CP-96,345 a nonpeptide substance P antagonist, capsaicin, resiniferatoxin and ruthenium red on nociception," Regulatory Peptides, vol.
Scintilla's lead program is resiniferatoxin for the treatment of intractable cancer pain.
Scintilla's lead program is resiniferatoxin ("RTX") to treat intractable cancer pain.
Sorrento is also producing resiniferatoxin, a non-opiate TRPV1 agonist presently in a Phase I/II trial at the NIH to treat terminal cancer patients suffering from intractable pain.