Specifically, patients with metastatic disease were primarily assigned to medical oncology, with radiation or surgery consulted for palliative reasons as needed; resectable
patients were primarily assigned to the surgical oncologist, seeing radiation and medical oncology afterward; and unresectable/borderline resectable
patients or technically resectable
patients with prohibitive cardiovascular/endocrine comorbidities were sent primarily to the radiation oncologist.
Similarly, for patients with potentially resectable
disease, surgical assessments may include identifying mutations that select patients with low recurrence risk and higher survival rates.
One strategy to improve the outcome for patients with resectable
pancreatic cancer is to treat them with adjuvant chemoradiation therapy following resection.
iii) those patients that are unlikely ever to become resectable
Chemotherapy is appropriate in patients whose liver disease is not resectable
, in cases where hepatic resection has a low likelihood of achieving a negative margin, and where disease is suspected elsewhere in the body, he said.
The results of the final IDM analysis that were submitted to the FDA are as follows: Six hundred and seventy eight (678) patients with newly diagnosed non-metastatic resectable
high grade osteosarcoma were treated with Junovan in combination with chemotherapy following surgery.
Unlike an immediate removal of the tumor, prolonged neoadjuvant therapy for resectable
cancer can be physically, socially, and emotionally difficult for patients, especially those with gynecologic malignancy.
Significant commercial reward awaits the developer of a therapy that is at least as effective as but safer and more tolerable than high dose interferon-alpha--Merck's Intron A--or PEG-interferon-alpha--Merck's Sylatron--in the adjuvant setting for resectable
malignant melanoma," said Decision Resources Analyst Rachel Webster, D.
However, a question still remains as to whether this 'oncosurgical' approach  should apply to all patients, especially to those with a single resectable
Javitt, director of women's imaging at Mercy Medical Center, Baltimore, noted that although CT may help determine whose cancer is resectable
, actually basing clinical decisions on such findings is another matter.
Following three months of treatment with BC-819 in the Phase I/IIa trial, five out of nine patients showed significant tumor reduction or stability, and two out of six patients in the higher dosage group became resectable
Abstract title: Monitoring Minimal Residual Disease by Urinary or Plasma Circulating Tumor DNA of KRAS Mutation Burden in Colorectal Cancer Patients with Resectable