replicon


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rep·li·con

(rep'li-kon),
1. A segment of a chromosome (or of the DNA of a chromosome or similar entity) that can replicate, with its own initiation and termination codons, independently of the chromosome in which it may be located.
2. The replication unit; several are found per DNA in eukaryotic systems.
[replication + -on]

replicon

(rĕp′lĭ-kŏn′)
n.
A genetic element that undergoes replication as an autonomous unit.

replicon

[rep′ləkon]
Etymology: L, replicare
a segment of DNA that is undergoing replication. It is regulated by a section of the molecule called the regulator, which controls replication and coordinates it with cell division.

rep·li·con

(rep'li-kon)
1. A segment of a chromosome (or of the DNA of a chromosome or similar entity) that can replicate, with its own initiation and termination codons, independently of the chromosome in which it may be located.
2. The replication unit; several are found per DNA in eukaryotic systems.
[replication + -on]

replicon

a DNA molecule containing an ORIGIN OF REPLICATION necessary for initiating REPLICATION.
References in periodicals archive ?
Replicon sequence typing of IncF plasmids carrying virulence and resistance determinants.
Biarri Networks plans to use Replicon to integrate with other applications, including its customer relationship management and project management systems.
As the co-founder and co-CEO of Replicon, she has is focused on strategic initiatives for Replicon's global operations, including market share expansion, revenue generation, and worldwide sales activities.
In HCV replicating cells, a translocation of the sMafs from the nucleus to the replicon complex occurs, where the sMafs bind to NS3 and thereby are withdrawn from the nucleus.
com), and Replicon ($22 per month per employee, replicon.
Their discovery comes in the same year as the 50th anniversary of a landmark in the field of DNA replication aACAo the presentation of the replicon model at the Cold Spring Harbor Symposium on DNA Replication in 1963 by FranEaA*ois Jacob, who was later awarded the Nobel Prize in Medicine.
Paragon Bioservices has been awarded a JVAP-CBMS contract from the Department of Defense (DoD) for the vaccine development and subsequent GMP manufacturing of the VEE Replicon Particle Trivalent Filovirus Vaccine.
compile 12 articles by researchers in virology, microbiology, infectious diseases, immunology, and related fields in North America, Europe, New Zealand, and Australia who detail current research findings on caliciviruses and related diseases, including norovirus epidemiology, calicivirus contamination of the environment, genome organization and recombination, proteolytic cleavage and viral proteins, viral protein structures, virus-host interactions, reverse genetics and replicon systems, feline calicivirus, murine noroviruses, and lagoviruses.
1998), inhibition of the host enzyme inosine monophosphate dehydrogenase (IMPDH) and reduction of HCV replicon colony-forming efficiency (Zhou et al.
HCV-subgenomic replicon systems (which allow HCV-RNA to replicate autonomously), have shown subcellular localization of core to be both cytoplasmic and nuclear (26,34).
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system.