replicative form


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rep·li·ca·tive form (RF),

1. an intermediate stage in the replication of either DNA or RNA viral genomes that is usually double stranded;
2. the altered, double-stranded form to which single-stranded coliphage DNA is converted after infection of a susceptible bacterium, formation of the complementary ("minus") strand being mediated by enzymes that were present in the bacterium before entrance of the viral ("plus") strand.
Farlex Partner Medical Dictionary © Farlex 2012

rep·li·ca·tive form

(rep'li-kă-tiv fōrm)
1. An intermediate stage in the replication of either DNA or RNA viral genomes that is usually double stranded.
2. The altered, double-stranded form to which single-stranded coliphage DNA is converted after infection of a susceptible bacterium, formation of the complementary ("minus") strand being mediated by enzymes that were present in the bacterium before entrance of the viral ("plus") strand.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive ?
Identification and characterization of type 2 dengue virus replicative intermediate and replicative form RNAs.
They made a single transfection of the VEE replicative form (RF) RNA into newborn or adult human fibroblasts, connective tissue cells that provide a structural framework for many other tissues.
We rather favour a model in which the double stranded replicative form of these phages is used for integration (Fig.