replicase


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rep·li·case

(rep'li-kās),
1. Descriptive term for RNA-directed RNA polymerase associated with replication of RNA viruses.
2. An enzyme that replicates nucleic acids.

replicase

/rep·li·case/ (rep´lĭ-kās)
1. a polymerase synthesizing RNA from an RNA template.
2. more generically, any enzyme that replicates nucleic acids, i.e., a DNA or RNA polymerase.

replicase

(rĕp′lĭ-kās′, -kāz′)
n.
Any of various enzymes that catalyze the synthesis of an RNA molecule from an RNA template (as in a virus) or a DNA molecule from a DNA template.

rep·li·case

(rep'li-kās)
Descriptive term for RNA-directed RNA polymerase (EC 2.7.7.48) associated with replication of RNA viruses.

replicase

or

RNA synthetase

an RNA-dependent RNA POLYMERASE ENZYME produced by some RNA VIRUSES for replication of the RNA genome.
References in periodicals archive ?
However, recent work with JHF1 viral RNA suggested that its 5'-NTR (+) does not contain RNA packaging signals (14) and authors further speculate that it may reside in the RNA region encoding the replicase.
Virions are enveloped and highly pleomorphic, with 50 to 200 nm in diameter, and a positive-sense ssRNA as genome, in which the 5' two-thrids (ORFs 1a and 1b) code for the replicase complex, highly conserved among members in each of the 3 groups the genus is divided, while the 3' final third codes for the structural proteins [2].
El Automated Q-Beta Replicase Amplification Assay[R] amplifica la subunidad 23 del ARN ribosomico de las micobacterias del complejo MTB; la sensibilidad ha sido del 84% y la especificidad, del 97%; permite obtener resultados en un maximo de 6,5 horas.
In the first section, they focus on the molecular biology of the virus itself and topics including coronavirus entry, replicase gene function, reverse genetics, genome packaging, and molecular evolution.
Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus.
The SARS-CoV has a RNA genome of 30 Kb encoding the replicase, spike glycoprotein, envelop protein, membrane protein, and nucleocapsid (2-4).
Resistance to wheat streak mosaic virus in transgenic wheat expressing the viral replicase (NIb) gene.
For the study, he and his associates developed PCR probes to target regions of the replicase la gene that are conserved among genetically diverse animal and human coronaviruses (J.
For the study, he and his associates developed PCR probes to target regions of the replicase 1a gene that are conserved among genetically diverse animal and human coronaviruses (J.
Moreover, the requirement of full-cDNAs, in vitro transcription of each one of the genomic RNAs and mix-and-match of each component along with the viral replicase makes this sort of experiments technically very difficult to perform.
Ithaca, NY) has patented a virus-induced resistance that may be transferred from one plant generation to another in which transgenic plants containing a coding sequence, taken from the read-through portion of the replicase portion of the viral genome, are resistant to subsequent disease by the virus.