Also, a DNA repair enzyme
derived from bacteria, T4 endonuclease V showed promise in an older study of 30 patients with xeroderma pigmentosum (Lancet.
of Gladstone Institute of Neurological Disease, San Francisco, and her colleagues found low levels of BRCA1 protein, a DNA repair enzyme
, in the brains of deceased Alzheimer's and mild cognitive impairment patients, compared with controls, as well as in mouse models of Alzheimer's.
A new approach to photoprotection is to repair DNA damage after UV exposure by delivering a DNA repair enzyme
into the skin by means of specially engineered liposomes.
For many years, scientists have known that viruses rely on functions provided by their host cells to increase their numbers, but the UCI study - led by microbiology and molecular genetics professor Bert Semler - is the first to identify how the RNA-containing picornaviruses utilize a DNA repair enzyme
to do so.
The human OGG1 DNA repair enzyme
and its association with orolaryngeal cancer risk.
These results are similar to data obtained with the DNA repair enzyme
Ogg1 and indicate the dependence of inhibition on the presence of free metal ions in solution (Zharkov and Rosenquist 2002).
com)-- In real life, the discovery of telomerase, the DNA repair enzyme
for all plants and animals, was awarded the 2009 Nobel Prize in Medicine.
coli DNA repair enzyme
, MutM, has been shown to remove 7,8-dihydro-8-oxoguanine (8-oxoG), an oxidatively damaged form of guanine nucleotide.
Other experiments demonstrated that the actual telomeres in blood cells of caregivers were shorter than those of the controls, and that the level of telomerase repair enzyme
among caregivers was lower.
PARP-1 is an abundant nuclear protein and base excision repair enzyme
found in most cells, residing within the nucleus and mitochondria, but can be present in the cytoplasm as well.
Several SNPs and somatic mutations have been characterized in a human 8-hydroxyguanine glycosylase gene, OGG1, which codes for a DNA repair enzyme
responsible for excising 8-hydroxyguanine from damaged DNA (1, 2).
has announced that the National Cancer Institute intends to conduct a one-year clinical trial of its Dimericine, a topical liposomal DNA repair enzyme
, to reduce the rate of skin cancer in renal transplant patients.