effect of Tanshinone IIA, an active component of Salvia miltiorrhiza, on rats with chronic kidney disease.
effect of the antioxidant curcumin: Recent Findings.
effects of green tea extract on renin-angiotensinaldosterone system in chronic cyclosporine-treated rats.
These findings suggest that CLE has renoprotective
effects against heated oil-induced oxidation and renal injury, possibly mediated by its antioxidant properties that is rich in polyphenols.
Accordingly, this study aimed to assess the renoprotective
effects of DPP4i combined with ARBs in patients with type 2 DN whose hyperglycemia was not adequately controlled with insulin alone or in combination with oral antidiabetic agents at baseline.
 It is also uncertain whether amlodipine has any significant renoprotective
It is worthy to note that renal artery endothelial dysfunction in SHR rats was unchanged after 13 weeks of captopril treatment, suggesting that the endothelial function might not be involved in the renoprotective
effects of captopril on SHR rats.
"In contrast to the previously reported cohort who were enrolled while on steroid therapy, the patients in this study were steroid-free, and yet the magnitude of proteinuria reduction across both groups is consistent and likely to indicate a significant renoprotective
effect of OMS721 in IgAN, with a legacy effect again seen for months beyond cessation of OMS721 treatment.
(9,10) To the best of our knowledge, no investigations have been made on this prevention, although several previous studies have indicated its renoprotective
effects in other nephropathy models.
STAR (Stent Placement in Patients With Atherosclerotic Renal Artery Stenosis and Impaired Renal Function), an RCT, which enrolled a relatively small number of patients, also could not demonstrate the renoprotective
effects of PTRA in patients with RAS and impaired renal function .
Xie et al., "The renoprotective
effects of simvastatin and atorvastatin in patients with acute coronary syndrome undergoing percutaneous coronary intervention: an observational study," Medicine, vol.
Taken together, renoprotective
effects by MSC-derived secretomes might be mainly mediated by EV-containing mRNA, miRNA, and proteins through a variety of mechanisms.