renaturation


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re·na·tu·ra·tion

(rē'nā-tyū-rā'shŭn),
The conversion of a denatured and inactive macromolecule back to its natured and bioactive configuration.
Farlex Partner Medical Dictionary © Farlex 2012

renaturation

(rē-nā′chər-ā′shən)
n.
The process by which proteins or complementary strands of nucleic acids re-form their native conformations.

re·na′ture v.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

renaturation

(rē″nā″chŭ-rā′shŏn) [ re- + (de)naturation]
The reassembly of a molecule or the shape of a molecule, e.g., the rejoining of unraveled complementary strands of DNA into a double helix.
renature (rē-nā′chŭr) renatured (rē-nā′chŭrd)
Medical Dictionary, © 2009 Farlex and Partners
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References in periodicals archive ?
Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli.
Following the renaturation and purification using heparin column, 0.5 [micro]g of eluted protein samples (monomer and dimer) was analyzed by NuPAGE gel electrophoresis as shown (b).
Expression, purification and renaturation of truncated human integrin b1 from inclusion bodies of Escherichia coli.
By renaturation after denaturation, it is found that the a-amylase activity with higher DE dextrin as carbon source was still higher than that of lower DE dextrin.
Renaturation of industrial sites specifically provides new areas for human recreation and, simultaneously, new habitats for many plant and animal species.
After electrophoresis, protein renaturation of the gel was induced twice using renaturation buffer (2.5% Triton X-100, 1 xPBS) for 20 min, and the gel was washed with sterilized water for 20 min.
Additionally, the present invention includes a method for the handling of denatured proteins with subsequent renaturation in situ (parenthetically after binding to metal charged iminodiacetic acid cellulose).
Since there are 9 disulfide bonds, renaturation of reteplase is very difficult with low efficiency (11-14).
The amplified products (5 [micro]L) from both controls and patients were mixed and subjected to denaturation and renaturation cycles.